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Home cDNA Clone TrueORF All ASIC2 ORF Clones
TrueORF Gold

ASIC2 (NM_001094) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC210409 ASIC2 (Myc-DDK-tagged)-Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, 10µg
$540
In Stock
RC510409 ASIC2 (Myc-DDK-tagged)-Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, (200ug) $660 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC210409L2 Lenti ORF clone of Human amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, mGFP tagged

1000 3 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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Also for ASIC2 (NM_001094)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC210409
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1539 bp
Predicted Protein MW: 57.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Ion Channels: OtherDruggable Genome
Protein Pathways: Taste transduction
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_001094.4, NP_001085
RefSeq Size: 2747 RefSeq ORF: 1539
Synonyms : ACCN; ACCN1; ASIC2a; BNaC1; BNC1; hBNaC1; MDEG
LocusID: 40 Cytogenetic: 17q12
Summary: This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 3 has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq, Feb 2012].

 

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