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Home cDNA Clone TrueORF All DIO1 ORF Clones

DIO1 (NM_001039716) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC205053 DIO1 (Myc-DDK-tagged)-Human deiodinase, iodothyronine, type I (DIO1), transcript variant 4, (Note, selenocysteine protein, internal stop codon, see reference data summary), 10µg   
390
$98
In Stock
RG205053 DIO1 (GFP-tagged) - Human deiodinase, iodothyronine, type I (DIO1), transcript variant 4, (10ug), (Note: selenocystein protein, Internal stop codon present. See Summary below) $430 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC505053 0 2 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG205053 DIO1 (GFP-tagged) - Human deiodinase, iodothyronine, type I (DIO1), transcript variant 4, (10ug), (Note: selenocystein protein, Internal stop codon present. See Summary below)

$430 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC205053
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 489 bp
Predicted Protein MW: 18.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneDruggable Genome

Reference Data
RefSeq Explanation: NM_001039716.1, NP_001034805 RefSeq Size: 1676 RefSeq ORF: 486
Synonyms : 5DI; TXDI1
LocusID: 1733 Cytogenetic: 1p32.3
Gene Summary: Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney. [UniProtKB/Swiss-Prot Function]

 

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