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Home cDNA Clone TrueORF All GLRB ORF Clones

GLRB (NM_000824) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC207619 GLRB (Myc-DDK-tagged)-Human glycine receptor, beta (GLRB), transcript variant 1, 10µg   
$560
In Stock
RG207619 GLRB (GFP-tagged) - Human glycine receptor, beta (GLRB), transcript variant 1, (10ug) $610 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC507619 0 2 weeks
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Clone Modification
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The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
RG207619 GLRB (GFP-tagged) - Human glycine receptor, beta (GLRB), transcript variant 1, (10ug)

$610 In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for RC207619
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1494 bp
Predicted Protein MW: 56.12 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: TransmembraneIon Channels: Cys-loop ReceptorsDruggable Genome
Protein Pathways: Neuroactive ligand-receptor interaction

Reference Data
RefSeq Explanation: NM_000824.2, NP_000815 RefSeq Size: 2649 RefSeq ORF: 1494
Synonyms : HKPX2
LocusID: 2743 Cytogenetic: 4q31.3 Domains: Neur_chan_memb, Neur_chan_LBD
Gene Summary: This gene encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009].

 

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