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Home cDNA Clone TrueORF All CHRNA4 ORF Clones
TrueORF Gold

CHRNA4 (NM_000744) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC214597 CHRNA4 (Myc-DDK-tagged)-Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4)
According to your current need cash now you really look at.
, 10µg
$540
In Stock
RC514597 CHRNA4 (Myc-DDK-tagged)-Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4), (200ug) $660 2~3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in Lenti and other vectors is also available.

Cat. No. Description Vector Price Availability  
RC214597L2 Lenti ORF clone of Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4), mGFP tagged

$1000 2 Weeks
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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Also for CHRNA4 (NM_000744)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody
TrueORF Data for RC214597
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1884 bp
Predicted Protein MW: 67.1 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Ion Channels: Cys-loop ReceptorsTransmembraneDruggable Genome
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_000744.2, NP_000735
RefSeq Size: 3773 RefSeq ORF: 1884
Synonyms : BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4
LocusID: 1137 Cytogenetic: 20q13.33
Summary: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb

 

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