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Home cDNA Clone TrueORF All CHRNA4 ORF Clones

CHRNA4 (NM_000744) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC214597 CHRNA4 (Myc-DDK-tagged)-Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4), 10µg   
$560
In Stock
RG214597 CHRNA4 (GFP-tagged) - Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4), (10ug) $610 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC514597 CHRNA4 (Myc-DDK-tagged)-Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4), (200ug) $680 2 weeks
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Clone Modification
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The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RC214597L1 Lenti ORF clone of Human cholinergic receptor, nicotinic, alpha 4 (CHRNA4) , Myc-DDK-tagged

$740 In Stock
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
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TrueORF Data for RC214597
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1884 bp
Predicted Protein MW: 69.96 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Ion Channels: Cys-loop ReceptorsTransmembraneDruggable Genome

Reference Data
RefSeq Explanation: NM_000744.2, NP_000735 RefSeq Size: 3773 RefSeq ORF: 1884
Synonyms : BFNC; EBN; EBN1; NACHR; NACHRA4; NACRA4
LocusID: 1137 Cytogenetic: 20q13.33
Gene Summary: This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012].

 

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