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Home cDNA Clone TrueORF All NOS2 ORF Clones

NOS2 (NM_000625) Human cDNA ORF Clone

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Cat. No. Description Price Availability  
RG211819 NOS2 (GFP-tagged) - Human nitric oxide synthase 2, inducible (NOS2), 10µg   
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TrueORF Data for RG211819
Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3462 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Druggable Genome
Protein Pathways: Arginine and proline metabolismMetabolic pathwaysCalcium signaling pathwayLong-term depressionAlzheimer's diseaseAmyotrophic lateral sclerosis (ALS)More Pathways >>

Reference Data
RefSeq Explanation: NM_000625.3, NP_000616 RefSeq Size: 4221 RefSeq ORF: 3462
Synonyms : HEP-NOS; INOS; NOS; NOS2A
LocusID: 4843 Cytogenetic: 17q11.2
Gene Summary: Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008].


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