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Home cDNA Clone TrueORF All TEK ORF Clones

TEK (NM_000459) Human cDNA ORF Clone

Western Blot Validated

Specifications Citations (1) Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC206554 TEK (Myc-DDK-tagged)-Human TEK tyrosine kinase, endothelial (TEK), 10µg   
800
$98
In Stock
RG206554 TEK (GFP-tagged) - Human TEK tyrosine kinase, endothelial (TEK), (10ug) $890 In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Cat. No. Description Price Availability
RC506554 0 2 weeks
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Clone Modification
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The same insert cloned in Lenti and other vectors are also available.

Cat. No. Description Vector Price Availability  
RC206554L1 Lenti ORF clone of Human TEK tyrosine kinase, endothelial (TEK) , Myc-DDK-tagged

$980 In Stock
TR30022 Lenti-vpak packaging kit - packaging plasmids and transfection reagent (10 rxns) Lenti-vpak-app-guide $390 In Stock
Lenti particle icon Add to Shopping Cart
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TrueORF Data for RC206554
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3375 bp
Predicted Protein MW: 125.8 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome

Reference Data
RefSeq Explanation: NM_000459.1, NP_000450 RefSeq Size: 4138 RefSeq ORF: 3375
Synonyms : CD202B; TIE-2; TIE2; VMCM; VMCM1
LocusID: 7010 Cytogenetic: 9p21 Domains: pkinase, TyrKc, S_TKc, FN3, EGF, EGF
Gene Summary: This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014].

 

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