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Home cDNA Clone TrueORF All MYL2 ORF Clones

MYL2 (NM_000432) Human cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RG205932 MYL2 (GFP-tagged) - Human myosin, light chain 2, regulatory, cardiac, slow (MYL2), 10µg
$420
In Stock
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for MYL2 (NM_000432)
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TrueORF Data for RG205932
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Vector: pCMV6-AC-GFP   Change vector? Tag: C-terminal TurboGFP
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 501 bp
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Pathways: Cardiac muscle contractionFocal adhesionTight junctionLeukocyte transendothelial migrationRegulation of actin cytoskeletonHypertrophic cardiomyopathy (HCM)More Pathways >>

Reference Data
RefSeq: NM_000432.1, NP_000423
RefSeq Size: 813 RefSeq ORF: 501
Synonyms : CMH10; MLC2
LocusID: 4633 Cytogenetic: 12q24.11 Domains: efhand
Summary: Thus gene encodes the regulatory light chain associated with cardiac myosin beta (or slow) heavy chain. Ca+ triggers the phosphorylation of regulatory light chain that in turn triggers contraction. Mutations in this gene are associated with mid-left ventricular chamber type hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008].

 

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