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Home cDNA Clone TrueORF All AURKA ORF Clones

AURKA (NM_198433) Human Mutant ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC403785 AURKA Mutant (F31I), Myc-DDK-tagged ORF clone of Homo sapiens aurora kinase A (AURKA), transcript variant 1 as transfection-ready DNA, 10µg
$600
1-2 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for AURKA (NM_198433)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC403785
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 1209 bp
Predicted Protein MW: 44.299999999999997 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation:
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseStem cell - PluripotencyDruggable Genome
Protein Pathways: Oocyte meiosis
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: , NP_940835
RefSeq Size: 1209 RefSeq ORF: 1212
Synonyms : AIK; ARK1; AURA; AURORA2; BTAK; PPP1R47; STK15; STK6; STK7
LocusID: 6790 Cytogenetic: 20q13
Summary: The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

 

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