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Home cDNA Clone TrueORF All STAT1 ORF Clones

STAT1 (NM_007315) Human Mutant ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC403201 STAT1 Mutant (E320Q), Myc-DDK-tagged ORF clone of Homo sapiens signal transducer and activator of transcription 1, 91kDa (STAT1), transcript variant alpha as transfection-ready DNA, 10µg
$1130
2-3 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for STAT1 (NM_007315)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC403201
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 2250 bp
Predicted Protein MW: 82.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation:
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transcription FactorsDruggable Genome
Protein Pathways: Chemokine signaling pathwayToll-like receptor signaling pathwayJak-STAT signaling pathwayPathways in cancerPancreatic cancer

Reference Data
RefSeq: , NP_009330
RefSeq Size: 2250 RefSeq ORF: 2253
Synonyms : CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
LocusID: 6772 Cytogenetic: 2q32.2 Domains: SH2, STAT_bind
Summary: The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008].

 

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