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Home cDNA Clone TrueORF All BUB1B ORF Clones

BUB1B (NM_001211) Human Mutant ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC402562 BUB1B Mutant (R224X), Myc-DDK-tagged ORF clone of Homo sapiens budding uninhibited by benzimidazoles 1 homolog beta (yeast) (BUB1B) as transfection-ready DNA, 10µg
$380
1-2 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for BUB1B (NM_001211)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
TrueORF Data for RC402562
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 669 bp
Predicted Protein MW: 24.5 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation:
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseStem cell - PluripotencyDruggable Genome
Protein Pathways: Cell cycle

Reference Data
RefSeq: , NP_001202
RefSeq Size: 669 RefSeq ORF: 3153
Synonyms : Bub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1
LocusID: 701 Cytogenetic: 15q15
Summary: This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq, Jul 2008].

 

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