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Home cDNA Clone TrueORF All AURKC ORF Clones

AURKC (NM_001015878) Human Mutant ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
RC402545 AURKC Mutant (Y248X), Myc-DDK-tagged ORF clone of Homo sapiens aurora kinase C (AURKC), transcript variant 1 as transfection-ready DNA, 10µg
$380
1-2 weeks
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification
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Also for AURKC (NM_001015878)
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TrueORF Data for RC402545
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Vector: pCMV6-Entry   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 741 bp
Predicted Protein MW: 27.2 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation:
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Protein KinaseDruggable Genome

Reference Data
RefSeq: , NP_001015878
RefSeq Size: 741 RefSeq ORF: 930
Synonyms : AIE2; AIK3; ARK3; AurC; aurora-C; SPGF5; STK13
LocusID: 6795 Cytogenetic: 19q13.43
Summary: This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

 

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