Home All Cancer Mutant Clones PIK3CA Mutants

Description of the mutations of PIK3CA (NM_006218) Mutants

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion

R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

SKU	Mutation Description	Affected Codon#	Affected NT#	Description	Effect
RC400346	E542K	542	c.1624	G>A	Missense
RC400347	E542V	542	c.1625	A>T	Missense
RC400348	E545K	545	c.1633	G>A	Missense
RC400349	E545G	545	c.1634	A>G	Missense
RC400350	E545A	545	c.1634	A>C	Missense
RC400351	E545D	545	c.1635	G>T	Missense
RC400352	E545Q	545	c.1633	G>C	Missense
RC400353	E135D	135	c.405	A>T	Missense
RC400354	E135R	135	c.403_404	GA>CG	Missense
RC400355	E135P	135	c.403_404	GA>CC	Missense
RC400356	H1047R	1047	c.3140	A>G	Missense
RC400357	H1047L	1047	c.3140	A>T	Missense
RC400358	G1007R	1007	c.3019	G>C	Missense
RC400359	T1025N	1025	c.3074	C>A	Missense
RC400360	T1025T	1025	c.3075	C>T	Missense
RC400361	T1025S	1025	c.3073	A>T	Missense
RC400362	T1025A	1025	c.3073	A>G	Missense
RC400363	T1025I	1025	c.3074	C>T	Missense
RC400364	P539R	539	c.1616	C>G	Missense
RC400365	R1023Q	1023	c.3068	G>A	Missense
RC400366	M1043V	1043	c.3127	A>G	Missense
RC400367	D549N	549	c.1645	G>A	Missense
RC400368	H1048Y	1048	c.3142	C>T	Missense
RC400369	A987V	987	c.2960	C>T	Missense
RC400370	M1004I	1004	c.3012	G>A	Missense
RC400371	L1026P	1026	c.3077	T>C	Missense
RC400372	Q546K	546	c.1636	C>A	Missense
RC400373	Q546R	546	c.1637	A>G	Missense
RC400374	Q546P	546	c.1637	A>C	Missense
RC400375	Q546L	546	c.1637	A>T	Missense
RC400376	Q546H	546	c.1638	G>T	Missense
RC400377	Q546E	546	c.1636	C>G	Missense
RC400378	W552G	552	c.1654	T>G	Missense
RC400379	S1015F	1015	c.3044	C>T	Missense
RC400380	E522K	522	c.1564	G>A	Missense
RC400381	G1049S	1049	c.3145	G>A	Missense
RC400382	G1049R	1049	c.3145	G>C	Missense
RC400383	G1049A	1049	c.3146	G>C	Missense
RC400384	L1001I	1001	c.3001	C>A	Missense
RC400385	G1050D	1050	c.3149	G>A	Missense
RC400386	I1062V	1062	c.3184	A>G	Missense
RC400387	F1039L	1039	c.3115	T>C	Missense
RC400388	Y1021C	1021	c.3062	A>G	Missense
RC400389	H1065L	1065	c.3194	A>T	Missense
RC400390	T1052K	1052	c.3155	C>A	Missense
RC400391	M1043I	1043	c.3129	G>T	Missense
RC400392	H1047Y	1047	c.3139	C>T	Missense
RC400393	E545D	545	c.1635	G>C	Missense
RC400394	G106V	106	c.317	G>T	Missense
RC400395	R38H	38	c.113	G>A	Missense
RC400396	R93W	93	c.277	C>T	Missense
RC400397	R108H	108	c.323	G>A	Missense
RC400398	E542Q	542	c.1624	G>C	Missense
RC400399	N1044D	1044	c.3130	A>G	Missense
RC400400	N1044K	1044	c.3132	T>A	Missense
RC400401	N345K	345	c.1035	T>A	Missense
RC400402	A1035V	1035	c.3104	C>T	Missense
RC400403	G1009E	1009	c.3026	G>A	Missense
RC400404	A1066V	1066	c.3197	C>T	Missense
RC400405	K111E	111	c.331	A>G	Missense
RC400406	K111N	111	c.333	G>C	Missense
RC400407	M1043T	1043	c.3128	T>C	Missense
RC400408	N1068fs*4	1068	c.3204_3205	insA	Frameshift
RC400409	E453K	453	c.1357	G>A	Missense
RC400410	H701P	701	c.2102	A>C	Missense
RC400411	C378R	378	c.1132	T>C	Missense
RC400412	C901F	901	c.2702	G>T	Missense

Over 1000 citations of OriGene cDNA clones

Description of the mutations of PIK3CA (NM_006218) Mutants