OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
HomeAll Cancer Mutant ClonesMLH1 Mutants

Description of the mutations of MLH1 (NM_000249) Mutants

Keys for Mutation Description

A.A. substitution
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted

 

SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC400338 Q62K62c.184C>AMissense
RC400339 N64S64c.190_191AA>TCMissense
RC400340 G67R67c.199G>CMissense
RC400341 G67E67c.200G>AMissense
RC400342 G67W67c.199G>TMissense
RC400343 C77R77c.231T>CMissense
RC400344 E78K78c.232G>AMissense
RC400345 V716M716c.2146G>AMissense
RC401472 S2X25C>AColorel ner, non-polyposis
RC401473 R18C1852C>TColorel ner, non-polyposis
RC401474 I19F1955A>TColorel ner, non-polyposis
RC401475 A21V2162C>TColorel ner, non-polyposis
RC401476 G22A2265G>CColorel ner
RC401477 E23D2369A>TColorel ner
RC401478 E23X2367G>TColorel ner, non-polyposis
RC401479 E23K2367G>AColorel ner, non-polyposis
RC401480 I25T2574T>CColorel ner
RC401481 I25F2573A>TColorel ner, non-polyposis
RC401482 Q26X2676C>TColorel ner, non-polyposis
RC401483 P28L2883C>TColorel ner, non-polyposis
RC401484 A29S2985G>TColorel ner, non-polyposis
RC401485 M35K35104T>AColorel ner, non-polyposis
RC401486 M35R35104T>GColorel ner, non-polyposis
RC401487 I36N36107T>AColorel ner, non-polyposis
RC401488 E37X37109G>TColorel ner, non-polyposis
RC401489 N38S38113A>GColorel ner, non-polyposis
RC401490 N38H38112A>CColorel ner, non-polyposis
RC401491 D41G41122A>GColorel ner, non-polyposis
RC401492 S44F44131C>TColorel ner, non-polyposis
RC401493 S46I46137G>TColorel ner, non-polyposis
RC401494 V49E49146T>AColorel ner, non-polyposis
RC401495 Q62X62184C>TColorel ner, non-polyposis
RC401496 D63E63189C>AColorel ner, non-polyposis
RC401497 D63N63187G>AColorel ner, non-polyposis
RC401498 G65D65194G>AColorel ner, non-polyposis
RC401499 I68N68203T>AColorel ner, non-polyposis
RC401500 E71X71211G>TColorel ner, non-polyposis
RC401501 C77Y77230G>AColorel ner, non-polyposis
RC401502 F80V80238T>GColorel ner, non-polyposis
RC401503 T82I82245C>TColorel ner, non-polyposis
RC401504 K84E84250A>GColorel ner, non-polyposis
RC401505 Q86X86256C>TColorel ner, non-polyposis
RC401506 E89X89265G>TColorel ner, non-polyposis
RC401507 S93G93277A>GColorel ner, non-polyposis
RC401508 Y97X97291T>GColorel ner, youn-onse
RC401509 R100P100299G>CColorel ner
RC401510 R100X100298C>TColorel ner, non-polyposis
RC401511 G101D101302G>AColorel ner, non-polyposis
RC401512 E102D102306G>TColorel ner
RC401513 E102K102304G>AColorel ner, non-polyposis
RC401514 S106R106318C>GGsri ner
RC401515 S106R106318C>AColorel ner, non-polyposis
RC401516 I107R107320T>GColorel ner, non-polyposis
RC401517 H109Q109327T>GGsri ner
RC401518 A111V111332C>TColorel ner, non-polyposis
RC401519 V113D113338T>AColorel ner, non-polyposis
RC401520 T117R117350C>GColorel ner, non-polyposis
RC401521 T117M117350C>TColorel ner, non-polyposis
RC401522 G122X122364G>TColorel ner, non-polyposis
RC401523 K123X123367A>TColorel ner, non-polyposis
RC401524 Y126X126378C>GColorel ner, non-polyposis
RC401525 A128P128382G>CColorel ner, non-polyposis
RC401526 S131X131392C>AColorel ner, non-polyposis
RC401527 D132H132394G>CColorel ner, non-polyposis
RC401528 G133X133397G>TColorel ner, non-polyposis
RC401529 L135V135403C>GColorel ner, non-polyposis
RC401530 P141A141421C>GColorel ner, non-polyposis
RC401531 Q146X146436C>TColorel ner, non-polyposis
RC401532 L155R155464T>GColorel ner, non-polyposis
RC401533 A160V160479C>TColorel ner
RC401534 L166F166498A>CColorel ner, non-polyposis
RC401535 L166X166497T>AColorel ner, non-polyposis
RC401536 R182K182545G>AColorel ner, non-polyposis
RC401537 R182G182544A>GColorel ner, non-polyposis
RC401538 V185G185554T>GColorel ner, non-polyposis
RC401539 S191I191572G>TColorel ner, non-polyposis
RC401540 S193X193578C>GColorel ner, non-polyposis
RC401541 S193P193577T>CColorel ner, non-polyposis
RC401542 K196X196586A>TColorel ner, non-polyposis
RC401543 E199Q199595G>CColorel ner, non-polyposis
RC401544 V213M213637G>AColorel ner, non-polyposis
RC401545 R217C217649C>TColorel ner, non-polyposis
RC401546 I219V219655A>GColorel ner, non-polyposis
RC401547 R226Q226677G>AColorel ner, non-polyposis
RC401548 R226L226677G>TColorel ner, non-polyposis
RC401549 R226X226676C>TColorel ner, non-polyposis
RC401550 E234G234701A>GColorel ner, non-polyposis
RC401551 G244D244731G>AColorel ner, non-polyposis
RC401552 S247P247739T>CColorel ner, non-polyposis
RC401553 S252X252755C>AColorel ner, non-polyposis
RC401554 L260R260779T>GColorel ner
RC401555 H264R264791A>GColorel ner
RC401556 H264Y264790C>TColorel ner, non-polyposis
RC401557 R265H265794G>AColorel ner, non-polyposis
RC401558 R265C265793C>TColorel ner, non-polyposis
RC401559 R265S265793C>AColorel ner, non-polyposis
RC401560 E268G268803A>GColorel ner, non-polyposis
RC401561 S269X269806C>GColorel ner, non-polyposis
RC401562 L272V272814T>GColorel ner
RC401563 Y280X280840T>AColorel ner, non-polyposis
RC401564 Y280D280838T>GColorel ner, non-polyposis
RC401565 A281V281842C>TColorel ner
RC401566 A282G282845C>GColorel ner, non-polyposis
RC401567 L284X284851T>AColorel ner, non-polyposis
RC401568 K286Q286856A>CColorel ner, non-polyposis
RC401569 L292P292875T>CColorel ner, non-polyposis
RC401570 Y293D293877T>GColorel ner, non-polyposis
RC401571 S295T295884G>CColorel ner, non-polyposis
RC401572 L296X296887T>GColorel ner, non-polyposis
RC401573 E297X297889G>TColorel ner, non-polyposis
RC401574 Q301X301901C>TColorel ner, non-polyposis
RC401575 V303E303908T>AColorel ner, non-polyposis
RC401576 D304V304911A>TColorel ner, non-polyposis
RC401577 L317M317949C>AColorel ner, non-polyposis
RC401578 E319X319955G>TColorel ner, non-polyposis
RC401579 S321I321962G>TColorel ner, non-polyposis
RC401580 V326A326977T>CColorel ner, non-polyposis
RC401581 H329P329986A>CColorel ner, non-polyposis
RC401582 H329N329985C>AColorel ner, non-polyposis
RC401583 N338S3381013A>GColorel ner, non-polyposis
RC401584 A353V3531058C>TColorel ner, non-polyposis
RC401585 T364A3641090A>GColorel ner, non-polyposis
RC401586 Y379C3791136A>GColorel ner, non-polyposis
RC401587 V384D3841151T>AColorel ner, non-polyposis
RC401588 R385P3851154G>CColorel ner, non-polyposis
RC401589 R385C3851153C>TColorel ner, non-polyposis
RC401590 R389Q3891166G>AColorel ner
RC401591 Q398X3981192C>TColorel ner, non-polyposis
RC401592 L400V4001198C>GColorel ner, non-polyposis
RC401593 S406N4061217G>AColorel ner, non-polyposis
RC401594 Q409X4091225C>TColorel ner, non-polyposis
RC401595 T413I4131238C>TColorel ner
RC401596 K416E4161246A>GColorel ner, non-polyposis
RC401597 S420C4201259C>GColorel ner
RC401598 Q426X4261276C>TColorel ner, non-polyposis
RC401599 A441T4411321G>AColorel ner, non-polyposis
RC401600 K443Q4431327A>CColorel ner, non-polyposis
RC401601 G454R4541360G>CColorel ner, non-polyposis
RC401602 M458K4581373T>AColorel ner, non-polyposis
RC401603 K461X4611381A>TColorel ner, non-polyposis
RC401604 R472I4721415G>TColorel ner
RC401605 R474Q4741421G>AColorel ner, non-polyposis
RC401606 D485E4851455T>AColorel ner, non-polyposis
RC401607 D485H4851453G>CColorel ner, non-polyposis
RC401608 R487X4871459C>TColorel ner, non-polyposis
RC401609 A492T4921474G>AColorel ner, non-polyposis
RC401610 P496L4961487C>TColorel ner
RC401611 V506A5061517T>CColorel ner, non-polyposis
RC401612 Q510X5101528C>TColorel ner, non-polyposis
RC401613 E512X5121534G>TColorel ner, non-polyposis
RC401614 G517X5171549G>TColorel ner, non-polyposis
RC401615 Q537X5371609C>TColorel ner, non-polyposis
RC401616 W538X5381614G>AColorel ner, non-polyposis
RC401617 Q542P5421625A>CColorel ner, non-polyposis
RC401618 Q542L5421625A>TColorel ner, non-polyposis
RC401619 Q542X5421624C>TColorel ner, non-polyposis
RC401620 L547X5471640T>AColorel ner, non-polyposis
RC401621 Y548X5481644C>AColorel ner, non-polyposis
RC401622 L549P5491646T>CColorel ner, non-polyposis
RC401623 L550P5501649T>CColorel ner, non-polyposis
RC401624 N551T5511652A>CColorel ner, non-polyposis
RC401625 E557X5571669G>TColorel ner, non-polyposis
RC401626 E558X5581672G>TColorel ner, non-polyposis
RC401627 L559R5591676T>GColorel ner, non-polyposis
RC401628 Y561X5611683C>GColorel ner, non-polyposis
RC401629 Y561H5611681T>CColorel ner, non-polyposis
RC401630 Q562X5621684C>TColorel ner, non-polyposis
RC401631 I565F5651693A>TColorel ner, non-polyposis
RC401632 L574P5741721T>CColorel ner, non-polyposis
RC401633 E578G5781733A>GColorel ner, non-polyposis
RC401634 P581L5811742C>TColorel ner, non-polyposis
RC401635 L582P5821745T>CColorel ner, non-polyposis
RC401636 L582V5821744C>GColorel ner, non-polyposis
RC401637 A586D5861757C>AColorel ner, non-polyposis
RC401638 A586P5861756G>CColorel ner, non-polyposis
RC401639 L588P5881763T>CColorel ner, non-polyposis
RC401640 A589D5891766C>AColorel ner, non-polyposis
RC401641 D601G6011802A>GColorel ner
RC401642 P603R6031808C>GColorel ner, non-polyposis
RC401643 K604X6041810A>TColorel ner, non-polyposis
RC401644 L607H6071820T>AColorel ner, non-polyposis
RC401645 A608D6081823C>AColorel ner, non-polyposis
RC401646 K618T6181853A>CColorel ner, non-polyposis
RC401647 K618E6181852A>GColorel ner, non-polyposis
RC401648 K618X6181852A>TColorel ner, non-polyposis
RC401649 L622H6221865T>AColorel ner, non-polyposis
RC401650 A623P6231867G>CColorel ner, non-polyposis
RC401651 Y625X6251875T>GColorel ner, non-polyposis
RC401652 D631A6311892A>CColorel ner, non-polyposis
RC401653 N635K6351905C>GGsri ner
RC401654 L636P6361907T>CColorel ner, non-polyposis
RC401655 P640S6401918C>TColorel ner, non-polyposis
RC401656 P640T6401918C>AColorel ner
RC401657 Y646C6461937A>GColorel ner, non-polyposis
RC401658 P648L6481943C>TColorel ner, non-polyposis
RC401659 P648S6481942C>TColorel ner, non-polyposis
RC401660 L653R6531958T>GColorel ner
RC401661 P654L6541961C>TColorel ner, non-polyposis
RC401662 I655T6551964T>CColorel ner, non-polyposis
RC401663 I655V6551963A>GEndomeril ner
RC401664 R659L6591976G>TColorel ner, non-polyposis
RC401665 R659Q6591976G>AColorel ner, non-polyposis
RC401666 R659P6591976G>CColorel ner, non-polyposis
RC401667 R659X6591975C>TColorel ner, non-polyposis
RC401668 T662P6621984A>CColorel ner, non-polyposis
RC401669 E663A6631988A>CColorel ner, non-polyposis
RC401670 W666X6661998G>AColorel ner, non-polyposis
RC401671 L676R6762027T>GColorel ner
RC401672 C680X6802040C>AColorel ner, non-polyposis
RC401673 C680R6802038T>CColorel ner, non-polyposis
RC401674 A681T6812041G>AColorel ner, non-polyposis
RC401675 R687W6872059C>TColorel ner, non-polyposis
RC401676 Q689R6892066A>GColorel ner, non-polyposis
RC401677 S692P6922074T>CColorel ner, non-polyposis
RC401678 S698X6982093C>GColorel ner, non-polyposis
RC401679 Q701X7012101C>TColorel ner, non-polyposis
RC401680 Q701K7012101C>AGsri ner
RC401681 W712X7122136G>AColorel ner, non-polyposis
RC401682 W712X7122135G>AColorel ner, non-polyposis
RC401683 W714X7142142G>AColorel ner, non-polyposis
RC401684 W714X7142141G>AColorel ner, non-polyposis
RC401685 H718Y7182152C>TColorel ner, non-polyposis
RC401686 Y721X7212163T>AColorel ner, non-polyposis
RC401687 L724M7242170T>AColorel ner, non-polyposis
RC401688 R725C7252173C>TColorel ner, non-polyposis
RC401689 L729V7292185C>GColorel ner
RC401690 K732X7322194A>TColorel ner, non-polyposis
RC401691 D737V7372210A>TColorel ner, non-polyposis
RC401692 L749P7492246T>CColorel ner
RC401693 Y750X7502250C>GColorel ner, non-polyposis
RC401694 K751R7512252A>GColorel ner, non-polyposis
RC401695 R755S7552265G>CColorel ner, non-polyposis
RC401696 R755W7552263A>TColorel ner, non-polyposis

 

bar
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title