Description of the mutations of GRK4 (NM_182982) Mutants
Keys for Mutation Description
A.A. substitution
Truncation
NT deletion
NT insertion
Truncation
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted
| SKU | Mutation Description | Affected Codon# | Affected NT# | Description | Effect |
| RC403752 | R65L | 65 | 194 | G>T | Aiviy, ssoiion wih |
| RC403753 | A142V | 142 | 425 | C>T | Aiviy, ssoiion wih |
| RC403754 | V486A | 486 | 1457 | T>C | Essenil hyperension, ssoiion wih |
