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HomeAll Cancer Mutant ClonesCTNNB1 Mutants

Description of the mutations of CTNNB1 (NM_001904) Mutants

Keys for Mutation Description

A.A. substitution
NT deletion
NT insertion
R280G: Arg at aa-position 280 mutated to Gly
R342X: R at aa-position 342 mutated to a stop codon and caused truncation of the protein
N268_D2: The deletion starts at nt#268. Two bases (including nt268) are deleted
N478-I6: The insertion starts after nt#478. Six bases are inserted


SKUMutation DescriptionAffected Codon#Affected NT#DescriptionEffect
RC400198 S45F45c.134C>TMissense
RC400199 S45A45c.133T>GMissense
RC400200 S45P45c.133T>CMissense
RC400201 S45Y45c.134C>AMissense
RC400202 S45C45c.134C>GMissense
RC400203 S45del45c.133_135delTCTdeletion
RC400204 D32G32c.95A>GMissense
RC400205 D32Y32c.94G>TMissense
RC400206 D32N32c.94G>AMissense
RC400207 D32V32c.95A>TMissense
RC400208 D32A32c.95A>CMissense
RC400209 D32H32c.94G>CMissense
RC400210 S33Y33c.98C>AMissense
RC400211 S33A33c.97T>G Missense
RC400212 S33P33c.97T>CMissense
RC400213 S33L33c.97_98TC>CTMissense
RC400214 G34V34c.101G>TMissense
RC400215 G34E34c.101G>AMissense
RC400216 R34R34c.100G>AMissense
RC400217 G48D48c.143G>AMissense
RC400218 E53K53c.157G>AMissense
RC400219 A43V43c.128C>TMissense
RC400220 G38D38c.113G>AMissense
RC400221 G38P38c.112_114GGT>CCCMissense
RC400222 S37F37c.110C>TMissense
RC400223 S37C37c.110C>GMissense
RC400224 S37Y37c.110C>AMissense
RC400225 S37P37c.109T>CMissense
RC400226 S37A37c.109T>GMissense
RC400227 T41A41c.121A>GMissense
RC400228 T41I41c.122C>TMissense
RC400229 H36P36c.107A>CMissense
RC400230 C619S619c.1855T>AMissense
RC400231 T40I40c.119C>TMissense
RC400232 H36Y36c.106C>TMissense
RC400233 I35S35c.104T>GMissense
RC400234 P44A44c.130C>GMissense
RC400235 A5_A80>D5c.14_241del228deletion
RC400236 T42R42c.125C>GMissense
RC400237 A43T43c.127G>AMissense
RC400238 D58N58c.172G>AMissense
RC400239 A21T21c.61G>AMissense
RC400240 S29F29c.86C>TMissense
RC400241 W25_D32del25c.74_97del24deletion
RC400242 A5_Q143del5c.14_430del417deletion
RC402574 N287S287860A>GColorectal adenoma?


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