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Home cDNA Clone TrueORF All Med12 ORF Clones

Med12 (NM_021521) Mouse cDNA ORF Clone

Specifications Citations Clones of Other Species Product Documents
Cat. No. Description Price Availability  
MR225918 Med12 (Myc-DDK-tagged) - Mouse mediator of RNA polymerase II transcription, subunit 12 homolog (yeast) (Med12), 10µg
In Stock
TA50011-100 4C5, Anti-DDK monoclonal antibody, 100µl $248 In Stock
Clone Modification

The same insert cloned in a GFP-tagging vector is also available

Cat. No. Description Vector Price Availability  
MG225918 GFP-tagged ORF clone of Mus musculus mediator of RNA polymerase II transcription subunit 12 homolog (yeast) (Med12) as transfection-ready DNA $3620 8 Weeks
TA150041 2H8, Anti-tGFP monoclonal antibody, 100µl Datasheet $248 In Stock
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TrueORF Data for MR225918
Vector: pCMV6-Entry2   Change vector? Tag: C-terminal Myc-DDK
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 6573 bp
Predicted Protein MW: 245 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene     Plasmid Map
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.

Reference Data
RefSeq: NM_021521.2, NP_067496
RefSeq Size: 8464 RefSeq ORF: 6573
Synonyms : 230kDa; Mopa; OPA-1; Tnrc11; Trap230
LocusID: 59024 Cytogenetic: X|X C2
Summary: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway. [UniProtKB/Swiss-Prot Function]


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