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Activation of Transcription Factor Nrf2 Signalling by the Sphingosine Kinase Inhibitor SKI-II Is Mediated by the Formation of Keap1 Dimers PLoS ONE, Feb 2014. [Keap1]

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TruePLEX™ ANGPT2 Single-plex Reagent Set

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Home >> TruePlex >> AM100106
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Catalog No. Product Description Amount Price Shipping *
AM100106 TruePLEX™ ANGPT2 Single-plex Reagent Set (Gene ID: 285) 96 rxn $229 2 weeks
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Product Details: Single-plex reagent set for the measurement of ANGPT2 in cell culture supernatant, human sera, or human plasma in conjunction with xMAP™ technology from Luminex Corporation. These reagents may be combined with other Growth Factor Panel single-plex reagent sets to create a custom multiplex. The TruePLEX™ Extracellular Core Reagent Kit (AM100097) kit is required to run this assay.
Standard Curves
11 plex standard curves
Gene Name: Angiopoietin 2
Research Focus: Oncology
Platform: Luminex xMAP®
Product Configuration: Single-plex can be mixed with up to 9 other single-plexes
Product Type: Single-plex reagent set
Sample Type: serum, plasma, tissue culture supernatant
Sample Volume: 50 µl
Species Reactivity: Human
Components: Beads, detection antibody, standards
Performance Summary
Performance Summary
Sensitivity Specification: 21 pg/ml
Normal Mean and Range Serum Samples: 1251.9 (82.5 - 10111)
Normal Mean and Range Plasma Samples: 818.1 (103.0 - 1706)
Intra-assay CV – Standards (specification): <15%
Intra-assay CV – Serum/Plasma (specification): <20%
Inter-assay CV – Serum/Plasma (specification): <20%
Recovery (specification) : 80-120%
Linearity (specification): 80-120%
Cross Reactivity: Negligible
Background Info: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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