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Aging Delays Resolution of Acute Inflammation in Mice: Reprogramming the Host Response with Novel Nanoproresolving Medicines J. Immunol. Sep 2014 [Alox15]

Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress J. Cell. Mol. Med. Sep 2014 [SOD2]

GADD45? induces G2/M arrest in human pharynx and nasopharyngeal carcinoma cells by cucurbitacin E Sci Rep Sep 2014 [GADD45G]

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TruePLEX™ HGF Single-plex Reagent Set

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Home >> TruePlex >> AM100104
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Catalog No. Product Description Amount Price Shipping *
AM100104 TruePLEX™ HGF Single-plex Reagent Set (Gene ID: 3082) 96 rxn $229 2 weeks
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Product Details: Single-plex reagent set for the measurement of HGF in cell culture supernatant, human sera, or human plasma in conjunction with xMAP™ technology from Luminex Corporation. These reagents may be combined with other Growth Factor Panel single-plex reagent sets to create a custom multiplex. The TruePLEX™ Extracellular Core Reagent Kit (AM100097) kit is required to run this assay.
Standard Curves
11 plex standard curves
Gene Name: Hepatocyte growth factor
Research Focus: Oncology
Platform: Luminex xMAP®
Product Configuration: Single-plex can be mixed with up to 9 other single-plexes
Product Type: Single-plex reagent set
Sample Type: serum, plasma, tissue culture supernatant
Sample Volume: 50 µl
Species Reactivity: Human
Components: Beads, detection antibody, standards
Performance Summary
Performance Summary
Sensitivity Specification: 14 pg/ml
Normal Mean and Range Serum Samples: 307.1 (11.9 - 843)
Normal Mean and Range Plasma Samples: 122.5 (37.3 - 239)
Intra-assay CV – Standards (specification): <15%
Intra-assay CV – Serum/Plasma (specification): <20%
Inter-assay CV – Serum/Plasma (specification): <20%
Recovery (specification) : 80-120%
Linearity (specification): 80-120%
Cross Reactivity: Negligible
Background Info: Hepatocyte growth factor regulates cell growth, cell motility, and morphogenesis by activating a tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. Its ability to stimulate mitogenesis, cell motility, and matrix invasion gives it a central role in angiogenesis, tumorogenesis, and tissue regeneration. It is secreted as a single inactive polypeptide and is cleaved by serine proteases into a 69-kDa alpha-chain and 34-kDa beta-chain. A disulfide bond between the alpha and beta chains produces the active, heterodimeric molecule. The protein belongs to the plasminogen subfamily of S1 peptidases but has no detectable protease activity. Alternative splicing of this gene produces multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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