OriGene - TruePlex TruePLEX™ PDGF-AB Single-plex Reagent Set

TruePLEX™ PDGF-AB Single-plex Reagent Set

Product Details: Single-plex reagent set for the measurement of PDGF-AB heterodimer in cell culture supernatant, human sera, or human plasma in conjunction with xMAP™ technology from Luminex Corporation. These reagents may be combined with other Growth Factor Panel single-plex reagent sets to create a custom multiplex. The TruePLEX™ Extracellular Core Reagent Kit (AM100097) kit is required to run this assay.

Standard Curves

Gene Name: Platelet-derived growth factor alpha polypeptide
Research Focus: Oncology
Platform: Luminex xMAP®
Product Configuration: Single-plex can be mixed with up to 9 other single-plexes
Product Type: Single-plex reagent set
Sample Type: serum, plasma, tissue culture supernatant
Sample Volume: 50 µl
Species Reactivity: Human
Components: Beads, detection antibody, standards

Performance Summary

Sensitivity Specification: 7 pg/ml
Normal Mean and Range Serum Samples: 924.9 (12.9 - 2014)
Normal Mean and Range Plasma Samples: 309.2 (7.8 - 941)
Intra-assay CV – Standards (specification): <15%
Intra-assay CV – Serum/Plasma (specification): <20%
Inter-assay CV – Serum/Plasma (specification): <20%
Recovery (specification) : 80-120%
Linearity (specification): 80-120%
Cross Reactivity: Negligible

Background Info: The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008].

OriGene Antibodies in recent publications

TruePLEX™ PDGF-AB Single-plex Reagent Set