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Home TrueClone PLP1 Clone

PLP1 (NM_199478) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC121107 PLP1 (untagged)-Human proteolipid protein 1 (PLP1), transcript variant 2, NM_199478.1, 10ug $390 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA317172 PLP1 Mouse anti-Bovine Monoclonal (C-Terminus) (plpc1) Antibody, 50ug $345 3-7 Days
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OriGene Data
Vector: pCMV6-XL5 Insert Size: Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: TransmembraneDruggable Genome
Reference Data
RefSeq Explanation: NM_199478.1, NP_955772
RefSeq Size: 2933 RefSeq ORF: 729
Synonyms : GPM6C; HLD1; MMPL; PLP; PLP/DM20; PMD; SPG2
LocusID: 5354 Cytogenetic: Xq22
Gene Summary: This gene encodes a transmembrane proteolipid protein that is the predominant component of myelin. The encoded protein may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively splicing results in multiple transcript variants, including the DM20 splice variant. [provided by RefSeq, Feb 2015].

Transcript Variant: This variant (2), also known as DM20, uses an alternate in-frame donor splice site at one of the coding exons compared to transcript variant 1. This results in a shorter isoform (2) missing an internal protein segment compared to isoform 1.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping


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