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Home TrueClone NEDD4 Clone

NEDD4 (NM_198400) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC123396 NEDD4 (untagged)-Human neural precursor cell expressed, developmentally down-regulated 4 (NEDD4), transcript variant 2, NM_198400.1, 10ug $2320 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA317057 NEDD4 Rabbit anti-Rat Polyclonal (aa395-462) Antibody, 50ul $345 3-7 Days
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OriGene Data
Vector: pCMV6-XL5 Insert Size: 5500 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: The ORF was fully sequenced and matches to NM_198400.1.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Ubiquitin mediated proteolysisEndocytosis
Reference Data
RefSeq Explanation: NM_198400.1, NP_940682
RefSeq Size: 7084 RefSeq ORF: 3744
Synonyms : NEDD4-1; RPF1
LocusID: 4734 Cytogenetic: 15q21.3
Gene Summary: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]

Transcript Variant: This variant (2) encodes isoform 2.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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