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Home TrueClone PPM1L Clone

PPM1L (NM_139245) Human cDNA Clone

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SKU Description Price Availibility*  
SC120685 PPM1L (untagged)-ORIGENE UNIQUE VARIANT 1 of Human protein phosphatase, Mg2+/Mn2+ dependent, 1L (PPM1L), NM_139245.2, 10ug $560 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA316170 Rabbit polyclonal anti-PPM1L antibody, 100ul $325 In Stock
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OriGene Data
Vector: pCMV6-XL4 Insert Size: 4000 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
OTI Disclaimer: The sequence of an 'OriGene Unique Variant' differs significantly from the associated reference. It represents a novel splice variant from the same gene locus of the reference. Although such variants are true transcripts and present opportunity for discoveries, they are not yet curated by NCBI and should not be used if the exact reference accession sequence is required.
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: PhosphataseDruggable Genome
Reference Data
RefSeq Explanation: NM_139245.2, NP_640338
RefSeq Size: 3056 RefSeq ORF: 1083
Synonyms : PP2C-epsilon; PP2CE; PPM1-LIKE
LocusID: 151742 Cytogenetic: 3q26.1 Domains: PP2Cc
Gene Summary: The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015].

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping


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