Over 1000 citations of OriGene cDNA clones

MET Receptor Sequence Variants R970C and T992I Lack Transforming Capacity Cancer Res., Aug 2010; 70: 6233 - 6237 [MET]

Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a Mol. Pharmacol., Aug 2010; 78: 226 - 236 [ZBTB10]

Tumor Lymphangiogenesis and Metastasis to Lymph Nodes Induced by Cancer Cell Expression of Podoplanin Am. J. Pathol., Aug 2010; 177: 1004 - 1016 [PDPN]

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2 Blood, Jul 2010; 116: 254 - 266 [RUNX1]

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EGLN2 (NM_053046) Human cDNA Clone

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Cat. No.

Ref. ID

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SC126989

NM_053046

Homo sapiens egl nine homolog 2 (C. elegans) (EGLN2), transcript variant 1 as transfection-ready DNA NM_053046.2

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Also for EGLN2 (NM_053046)

OriGene TrueClone Data

Vector:	pCMV6-XL6	Insert Size: 1800	Restriction Site: NotI-NotI
Sequence Data:	5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.

Reference Data

RefSeq: NM_053046.2, NP_444274	RefSeq Size: 2111	RefSeq ORF: 1224
Synonyms : DKFZp434E026; EIT6; HIFPH1; HPH-3; PHD1
LocusID: 112398	Cytogenetic: 19q13.2
Summary: The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this posttranslational modification. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]. Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. Both variants 1 and 3 utilize alternative start codons that result in expression of two isoforms known as PHD1p43 and PHD1p40.