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Home TrueClone GZMH Clone

GZMH (NM_033423) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC125566 GZMH (untagged)-Human granzyme H (cathepsin G-like 2, protein h-CCPX) (GZMH) (10ug), NM_033423.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA313990 Rabbit polyclonal anti-Granzyme H (GRAH) antibody, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ProteaseDruggable Genome
Reference Data
RefSeq: NM_033423.2, NP_219491
RefSeq Size: 1047 RefSeq ORF: 741
Synonyms : CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2
LocusID: 2999 Cytogenetic: 14q11.2
Summary: The protein encoded by this gene is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Jul 2012].

Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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