TLR9 (NM_017442) Human Untagged Clone

CAT#: SC122858

TLR9 (untagged)-Human toll-like receptor 9 (TLR9)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TLR9
• Synonyms: CD289
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_017442 edited
  CCACGCGTCCGGGGACCTCGAGTGTGAAGCATCCTTCCCTGTAGCTGCTGTCCAGTCTGC
  CCGCCAGACCCTCTGGAGAAGCCCCTGCCCCCCAGCATGGGTTTCTGCCGCAGCGCCCTG
  CACCCGCTGTCTCTCCTGGTGCAGGCCATCATGCTGGCCATGACCCTGGCCCTGGGTACC
  TTGCCTGCCTTCCTACCCTGTGAGCTCCAGCCCCACGGCCTGGTGAACTGCAACTGGCTG
  TTCCTGAAGTCTGTGCCCCACTTCTCCATGGCAGCACCCCGTGGCAATGTCACCAGCCTT
  TCCTTGTCCTCCAACCGCATCCACCACCTCCATGATTCTGACTTTGCCCACCTGCCCAGC
  CTGCGGCATCTCAACCTCAAGTGGAACTGCCCGCCGGTTGGCCTCAGCCCCATGCACTTC
  CCCTGCCACATGACCATCGAGCCCAGCACCTTCTTGGCTGTGCCCACCCTGGAAGAGCTA
  AACCTGAGCTACAACAACATCATGACTGTGCCTGCGCTGCCCAAATCCCTCATATCCCTG
  TCCCTCAGCCATACCAACATCCTGATGCTAGACTCTGCCAGCCTCGCCGGCCTGCATGCC
  CTGCGCTTCCTATTCATGGACGGCAACTGTTATTACAAGAACCCCTGCAGGCAGGCACTG
  GAGGTGGCCCCGGGTGCCCTCCTTGGCCTGGGCAACCTCACCCACCTGTCACTCAAGTAC
  AACAACCTCACTGTGGTGCCCCGCAACCTGCCTTCCAGCCTGGAGTATCTGCTGTTGTCC
  TACAACCGCATCGTCAAACTGGCGCCTGAGGACCTGGCCAATCTGACCGCCCTGCGTGTG
  CTCGATGTGGGCGGAAATTGCCGCCGCTGCGACCACGCTCCCAACCCCTGCATGGAGTGC
  CCTCGTCACTTCCCCCAGCTACATCCCGATACCTTCAGCCACCTGAGCCGTCTTGAAGGC
  CTGGTGTTGAAGGACAGTTCTCTCTCCTGGCTGAATGCCAGTTGGTTCCGTGGGCTGGGA
  AACCTCCGAGTGCTGGACCTGAGTGAGAACTTCCTCTACAAATGCATCACTAAAACCAAG
  GCCTTCCAGGGCCTAACACAGCTGCGCAAGCTTAACCTGTCCTTCAATTACCAAAAGAGG
  GTGTCCTTTGCCCACCTGTCTCTGGCCCCTTCCTTCGGGAGCCTGGTCGCCCTGAAGGAG
  CTGGACATGCACGGCATCTTCTTCCGCTCACTCGATGAGACCACGCTCCGGCCACTGGCC
  CGCCTGCCCATGCTCCAGACTCTGCGTCTGCAGATGAACTTCATCAACCAGGCCCAGCTC
  GGCATCTTCAGGGCCTTCCCTGGCCTGCGCTACGTGGACCTGTCGGACAACCGCATCAGC
  GGAGCTTCGGAGCTGACAGCCACCATGGGGGAGGCAGATGGAGGGGAGAAGGTCTGGCTG
  CAGCCTGGGGACCTTGCTCCGGCCCCAGTGGACACTCCCAGCTCTGAAGACTTCAGGCCC
  AACTGCAGCACCCTCAACTTCACCTTGGATCTGTCACGGAACAACCTGGTGACCGTGCAG
  CCGGAGATGTTTGCCCAGCTCTCGCACCTGCAGTGCCTGCGCCTGAGCCACAACTGCATC
  TCGCAGGCAGTCAATGGCTCCCAGTTCCTGCCGCTGACCGGTCTGCAGGTGCTAGACCTG
  TCCCACAATAAGCTGGACCTCTACCACGAGCACTCATTCACGGAGCTACCACGACTGGAG
  GCCCTGGACCTCAGCTACAACAGCCAGCCCTTTGGCATGCAGGGCGTGGGCCACAACTTC
  AGCTTCGTGGCTCACCTGCGCACCCTGCGCCACCTCAGCCTGGCCCACAACAACATCCAC
  AGCCAAGTGTCCCAGCAGCTCTGCAGTACGTCGCTGCGGGCCCTGGACTTCAGCGGCAAT
  GCACTGGGCCATATGTGGGCCGAGGGAGACCTCTATCTGCACTTCTTCCAAGGCCTGAGC
  GGTTTGATCTGGCTGGACTTGTCCCAGAACCGCCTGCACACCCTCCTGCCCCAAACCCTG
  CGCAACCTCCCCAAGAGCCTACAGGTGCTGCGTCTCCGTGACAATTACCTGGCCTTCTTT
  AAGTGGTGGAGCCTCCACTTCCTGCCCAAACTGGAAGTCCTCGACCTGGCAGGAAACCAG
  CTGAAGGCCCTGACCAATGGCAGCCTGCCTGCTGGCACCCGGCTCCGGAGGCTGGATGTC
  AGCTGCAACAGCATCAGCTTCGTGGCCCCCGGCTTCTTTTCCAAGGCCAAGGAGCTGCGA
  GAGCTCAACCTTAGCGCCAACGCCCTCAAGACAGTGGACCACTCCTGGTTTGGGCCCCTG
  GCGAGTGCCCTGCAAATACTAGATGTAAGCGCCAACCCTCTGCACTGCGCCTGTGGGGCG
  GCCTTTATGGACTTCCTGCTGGAGGTGCAGGCTGCCGTGCCCGGTCTGCCCAGCCGGGTG
  AAGTGTGGCAGTCCGGGCCAGCTCCAGGGCCTCAGCATCTTTGCACAGGACCTGCGCCTC
  TGCCTGGATGAGGCCCTCTCCTGGGACTGTTTCGCCCTCTCGCTGCTGGCTGTGGCTCTG
  GGCCTGGGTGTGCCCATGCTGCATCACCTCTGTGGCTGGGACCTCTGGTACTGCTTCCAC
  CTGTGCCTGGCCTGGCTTCCCTGGCGGGGGCGGCAAAGTGGGCGAGATGAGGATGCCCTG
  CCCTACGATGCCTTCGTGGTCTTCGACAAAACGCAGAGCGCAGTGGCAGACTGGGTGTAC
  AACGAGCTTCGGGGGCAGCTGGAGGAGTGCCGTGGGCGCTGGGCACTCCGCCTGTGCCTG
  GAGGAACGCGACTGGCTGCCTGGCAAAACCCTCTTTGAGAACCTGTGGGCCTCGGTCTAT
  GGCAGCCGCAAGACGCTGTTTGTGCTGGCCCACACGGACCGGGTCAGTGGTCTCTTGCGC
  GCCAGCTTCCTGCTGGCCCAGCAGCGCCTGCTGGAGGACCGCAAGGACGTCGTGGTGCTG
  GTGATCCTGAGCCCTGACGGCCGCCGCTCCCGCTACGTGCGGCTGCGCCAGCGCCTCTGC
  CGCCAGAGTGTCCTCCTCTGGCCCCACCAGCCCAGTGGTCAGCGCAGCTTCTGGGCCCAG
  CTGGGCATGGCCCTGACCAGGGACAACCACCACTTCTATAACCGGAACTTCTGCCAGGGA
  CCCACGGCCGAATAGCCGTGAGCCGGAATCCTGCACGGTGCCACCTCCACACTCACCTCA
  CCTCTGCCTGCCTGGTCTGACCCTCCCCTGCTCGCCTCCCTCACCCCACACCTGACACAG
  AGCAGGCACTCAATAAATGCTACCGAAGGCTAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017442 unedited
  NNNNAAAGTTCAGATTTTGTAATACGACTTCACTATAGGGCGGGCCGCGCAATTCCCGGG
  GTATCGTCGACCCACGCGTCCGGGGACCTCGAGTGTGAAGCATCCTTCCCTGTAGCTGCT
  GTCCAGTCTGCCCGCCAGACCCTCTGGAGAAGCCCCTGCCCCCCAGCATGGGTTTCTGCC
  GCAGCGCCCTGCACCCGCTGTCTCTCCTGGTGCAGGCCATCATGCTGGCCATGACCCTGG
  CCCTGGGTACCTTGCCTGCCTTCCTACCCTGTGAGCTCCAGCCCCACGGCCTGGTGAACT
  GCAACTGGCTGTTCCTGAAGTCTGTGCCCCACTTCTCCATGGCAGCACCCCGTGGCAATG
  TCACCAGCCTTTCCTTGTCCTCCAACCGCATCCACCACCTCCATGATTCTGACTTTGCCC
  ACCTGCCCAGCCTGCGGCATCTCAACCTCAAGTGGAACTGCCCGCCGGTTGGCCTCAGCC
  CCATGCACTTCCCCTGCCACATGACCATCGAGCCCAGCACCTTCTTGGCTGTGCCCACCC
  TGGAAGAGCTAAACCTGAGCTACAACAACATCATGACTGTGCCTGCGCTGCCCAAATCCC
  TCATATCCCTGTCCCTCAGCCATACCAACATCCTGATGCTAGACTCTGCCAGCCTCGCCG
  GCCTGCATGCCCTGCGCTTCCTATTCATGGACGGCAACTGTTATTACAAGAACCCCTGCA
  GGCAGGCACTGGAGGTGGCCCCGGGTGCCCCTCTTGGCCTGGGGCACCTCACCCACCTGT
  CACTCAAGTACAACAACCTCACTGTGGTGCCCCGGCACCTGCCCTTCAGCCCTGGAGTAT
  CTGCTGGTTGTCCTACAACCGCATCGTTCAACTGGGCGCCTGAGGACCTTGGCCAATCTG
  ACCGC
  
• Restriction Sites: Please inquire
• ACCN: NM_017442
• Insert Size: 3384 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_017442.2, NP_059138.1
• RefSeq Size: 3868 bp
• RefSeq ORF: 3099 bp
• Locus ID: 54106
• UniProt ID: Q9NR96
• Cytogenetics: 3p21.2
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Toll-like receptor signaling pathway
• Gene Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]
  Transcript Variant: This variant (A) is a biexonic transcript which encodes the longer isoform (A).