Adiponectin Receptor 1 (ADIPOR1) (NM_015999) Human Untagged Clone

CAT#: SC114483

ADIPOR1 (untagged)-Human adiponectin receptor 1 (ADIPOR1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Adiponectin Receptor 1
• Synonyms: ACDCR1; CGI-45; CGI45; PAQR1; TESBP1A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114483 sequence for NM_015999 edited (data generated by NextGen Sequencing)
  ATGTCTTCCCACAAAGGATCTGTGGTGGCACAGGGGAATGGGGCTCCTGCCAGTAACAGG
  GAAGCTGACACGGTGGAACTGGCTGAACTGGGACCCCTGCTAGAAGAGAAGGGCAAACGG
  GTAATCGCCAACCCACCCAAAGCTGAAGAAGAGCAAACATGCCCAGTGCCCCAGGAAGAA
  GAGGAGGAGGTGCGGGTACTGACACTTCCCCTGCAAGCCCACCACGCCATGGAGAAGATG
  GAAGAGTTTGTGTACAAGGTCTGGGAGGGACGTTGGAGGGTCATCCCATATGATGTGCTC
  CCTGACTGGCTAAAGGACAACGACTATCTGCTACATGGTCATAGACCTCCCATGCCCTCC
  TTTCGGGCTTGCTTCAAGAGCATCTTCCGCATTCATACAGAAACTGGCAACATCTGGACC
  CATCTGCTTGGTTTCGTGCTGTTTCTCTTTTTGGGAATCTTGACCATGCTCAGACCAAAT
  ATGTACTTCATGGCCCCTCTACAGGAGAAGGTGGTTTTTGGGATGTTCTTTTTGGGTGCA
  GTGCTCTGCCTCAGCTTCTCCTGGCTCTTTCACACCGTCTATTGTCATTCAGAGAAAGTC
  TCTCGGACTTTTTCCAAACTGGACTATTCAGGGATTGCTCTTCTAATTATGGGGAGCTTT
  GTCCCCTGGCTCTATTATTCCTTCTACTGCTCCCCACAGCCACGGCTCATCTACCTCTCC
  ATCGTCTGTGTCCTGGGCATTTCTGCCATCATTGTGGCGCAGTGGGACCGGTTTGCCACT
  CCTAAGCACCGGCAGACAAGAGCAGGCGTGTTCCTGGGACTTGGCTTGAGTGGCGTCGTG
  CCCACCATGCACTTTACTATCGCTGAGGGCTTTGTCAAGGCCACCACAGTGGGCCAGATG
  GGCTGGTTCTTCCTCATGGCTGTGATGTACATCACTGGAGCTGGCCTTTATGCTGCTCGA
  ATTCCTGAGCGCTTCTTTCCTGGAAAATTTGACATATGGTTCCAGTCTCATCAGATTTTC
  CATGTCCTGGTGGTGGCAGCAGCCTTTGTCCACTTCTATGGAGTCTCCAACCTTCAGGAA
  TTCCGTTACGGCCTAGAAGGCGGCTGTACTGATGACACCCTTCTCTGA
  
  Clone variation with respect to NM_015999.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015999 unedited
  GCGATTTTGTAAACCGACTTTACTATAGGCGGCCGCGCAATTCGCACGAGGGGCGCGGGG
  AGGGCGCTGAAGATCGGGGCCGCTCGGCCGCAGGCCGCCTCCAGCGCCGCGGGATGTAGC
  GCGGGGGACCGCGGCCCCCAGCAGAGCCCGCCTGCCCGGCTTGTCTACCATCAGAGGGAG
  ATCTCTGCCCCCTGGGGCTGAGAGACCCCAACCTTTCCCCAAGCTGAAGCTGCAGGGTAT
  TGAGGTACCAGCCAGATGTCTTCCCACAAAGGATCTGTGGTGGCACAGGGGAATGGGGCT
  CCTGCCAGTAACAGGGAAGCTGACACGGTGGAACTGGCTGAACTGGGACCCCTGCTAGAA
  GAGAAGGGCAAACGGGTAATCGCCAACCCACCCAAAGCTGAAGAAGAGCAAACATGCCCA
  GTGCCCCAGGAAGAAGAGGAGGAGGTGCGGGTACTGACACTTCCCCTGCAAGCCCACCAC
  GCCATGGAGAAGATGGAAGAGTTTGTGTACAAGGTCTGGGAGGGACGTTGGAGGGTCATC
  CCATATGATGTGCTCCCTGACTGGCTAAAGGACAACGACTATCTGCTACCATGGTCATAG
  ACCTCCCATGCCCCTCCTTTTCGGCTTGCTTCAAGAGCATCTTCCGCATTCATACAGAAA
  CTGGCAACATCTGGACCCATCTGCTTGCTTTCGTGCTGCTTCTCTTTTTGGGAATCTTGA
  CCCTGCTCAGACCAAAAATGTACTTTCTGGCCCCTCTCCCAGAGAACCCGGCTCTTGCGA
  CGTTCTTTTTGGGGCAAAGCTTTGCCTCACTTTTCCTGGCTCTTCACCCGTCTATGGTCA
  TTCAAAAAAGCTCTTTGGACTTTTCCCAAACTGGACTTTCAAGGGATCGCCCTTCTAAAT
  ATGGGGAACCTTGGCCCCTGGCCCTCATATTTCCTTCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015999 unedited
  TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTCTCTTCTGTACTT
  TCTTTTATTAACATCATAGTCTTTGCATCAAGATACATAGCAATGATAGCAGGTTTCTTT
  TTAAAGCTTAGTATTAAATATTAAATATCTTTCCCCATTTAAATTTTACATTACTCTGCC
  AAGAAAAAAAAAAAATTAAAACTCAAGTTACTTGAAGCCTGGACACACTTCCATGATTAG
  CCGGGCTAGGTAAAAGTTGGGGGCTTTATTCTTCCTGCTCTATAAGCAGATCCAGGCCCT
  AGAAAGATGGGACCAGGGTATATAATTGTTTTTGAAAAGTGTGCTACAAAAATGGATGGC
  CTGTTATAAGCCAGGATACAAAGTTAAGGATAGGGGTAAGGGAGGGACATTTTCTTCCAG
  AAGAAAAGACAGAATTTCTGAAGAGTCCCAGTCCATAATTTTCCCAAAATGGTTGGAGGA
  GAGGGTAAAATCTCAACATGAGTTTCAAAGTACTGTCTCTGTGAGGGGCCGGTAGATGCC
  TTGCTGAGGAGGGGATGGCTAAGTTTGACCATGCCCCATCCCCAGCTAGGAGAATGGAAA
  TGGAAAGTTTATTGCCCAGTGGGTGTGAAAGTGGGCTGAAGCTTGGTTGGTACTGAATTC
  TCTAAGAGGTTTCTTCTAGAAACAGACAACTCAGACTCTTCCTCTCACTTCAGCANAGAA
  GNTATTTTTAAAAGCACTTGGGAAGTTCCTCCTCCACCCCGCAGGTGGGAAGGCTCANAG
  AAGGGTGTCATCAGTACAGCCGNCCTCCTAGGCCCGTACGGAATTCCTCGAANTGGNAGA
  CTNCATAGAAGTGGACAAAGGCTGCTGCCACCACCAGNACTGGNAAATCTGATGAGACTG
  GGAACATATGTCCAATTTTCAGGAANGAACGCTCAGGATTCNAGCACATAAAGGCCGCTC
  AGTGATGACATCCAGCCATGAGGAGAACCGCCCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_015999
• Insert Size: 2000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_015999.2, NP_057083.2
• RefSeq Size: 2108 bp
• RefSeq ORF: 1128 bp
• Locus ID: 51094
• UniProt ID: Q96A54
• Cytogenetics: 1q32.1
• Domains: UPF0073
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Adipocytokine signaling pathway
• Gene Summary: This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014]
  Transcript Variant: This variant (1, also known as R1T1) is a predominant transcript. All variants encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.