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Home TrueClone CYP46A1 Clone

CYP46A1 (NM_006668) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC120806 CYP46A1 (untagged)-Human cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1) (10ug), NM_006668.1, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA301675 Rabbit Polyclonal Antibody against Cyp-46, 100ul $325 3-7 Days
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Also for CYP46A1 (NM_006668)
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 3850 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: P450Druggable Genome
Protein Pathways: Primary bile acid biosynthesis
Reference Data
RefSeq: NM_006668.1, NP_006659
RefSeq Size: 2138 RefSeq ORF: 1503
Synonyms : CP46; CYP46
LocusID: 10858 Cytogenetic: 14q32.1
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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