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Home TrueClone VAV3 Clone

VAV3 (NM_006113) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC116335 VAV3 (untagged)-Human vav 3 guanine nucleotide exchange factor (VAV3), transcript variant 1 (10ug), NM_006113.3, 10ug $1530 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA318222 VAV3 Goat Polyclonal (Internal) Antibody, 50ug $345 3-7 Days
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 5000 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: no
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Chemokine signaling pathwayFocal adhesionNatural killer cell mediated cytotoxicityT cell receptor signaling pathwayB cell receptor signaling pathwayFc epsilon RI signaling pathwayMore Pathways >>
Reference Data
RefSeq: NM_006113.3, NP_006104
RefSeq Size: 4768 RefSeq ORF: 2544
Synonyms : FLJ40431
LocusID: 10451 Cytogenetic: 1p13.3 Domains: RhoGEF, SH2, SH3, CH, PH, C1
Summary: This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (1, also known as VAV-3alpha) encodes the longer isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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