HNRPM (HNRNPM) (NM_005968) Human Untagged Clone

CAT#: SC111657

HNRNPM (untagged)-Human heterogeneous nuclear ribonucleoprotein M (HNRNPM), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HNRPM
• Synonyms: CEAR; hnRNP M; HNRNPM4; HNRPM; HNRPM4; HTGR1; NAGR1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_005968, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCAGGGGTCGAAGCGGCGGCGGAGGTGGCGGCGACGGAGATCAAAATGGAGGAAGAGAGCGGCG
  CGCCCGGCGTGCCGAGCGGCAACGGGGCTCCGGGCCCTAAGGGTGAAGGAGAACGACCTGCTCAGAATGA
  GAAGAGGAAGGAGAAAAACATAAAAAGAGGAGGCAATCGCTTTGAGCCATATGCCAATCCAACTAAAAGA
  TACAGAGCCTTCATTACAAACATACCTTTTGATGTGAAATGGCAGTCACTTAAAGACCTGGTTAAAGAAA
  AAGTTGGTGAGGTAACATACGTGGAGCTCTTAATGGACGCTGAAGGAAAGTCAAGGGGATGTGCTGTTGT
  TGAATTCAAGATGGAAGAGAGCATGAAAAAAGCTGCGGAAGTCCTAAACAAGCATAGTCTGAGCGGAAGA
  CCACTGAAAGTCAAAGAAGATCCTGATGGTGAACATGCCAGGAGAGCAATGCAAAAGGTGATGGCTACGA
  CTGGTGGGATGGGTATGGGACCAGGTGGCCCAGGAATGATTACTATCCCACCCAGTATCCTAAATAATCC
  CAACATCCCAAATGAGATTATCCATGCATTACAGGCTGGAAGACTTGGAAGCACAGTATTTGTAGCAAAT
  CTGGATTATAAAGTTGGCTGGAAGAAACTGAAGGAAGTATTTAGTATGGCTGGTGTGGTGGTCCGAGCAG
  ACATTCTTGAAGATAAAGATGGAAAAAGTCGTGGAATAGGCACTGTTACTTTTGAACAGTCCATTGAAGC
  TGTGCAAGCTATATCTATGTTCAATGGCCAGCTGCTATTTGATAGACCAATGCACGTCAAGATGGATGAG
  AGGGCCTTACCAAAAGGAGATTTCTTCCCTCCTGAGCGTCCACAACAACTTCCCCATGGCCTTGGTGGTA
  TTGGCATGGGGTTAGGACCAGGAGGGCAACCCATTGATGCCAATCACCTGAATAAAGGCATCGGAATGGG
  AAACATAGGTCCCGCAGGAATGGGAATGGAAGGCATAGGATTTGGAATAAATAAAATGGGAGGAATGGAG
  GGGCCCTTTGGTGGTGGTATGGAAAACATGGGTCGATTTGGATCTGGGATGAACATGGGCAGGATAAATG
  AAATCCTAAGTAATGCACTGAAGAGAGGAGAGATCATTGCAAAGCAGGGAGGAGGTGGAGGTGGAGGAAG
  CGTCCCTGGGATCGAGAGGATGGGTCCTGGCATTGACCGCCTCGGGGGTGCCGGCATGGAGCGCATGGGC
  GCGGGCCTGGGCCACGGCATGGATCGCGTGGGCTCCGAGATCGAGCGCATGGGCCTGGTCATGGACCGCA
  TGGGCTCCGTGGAGCGCATGGGCTCCGGCATTGAGCGCATGGGCCCGCTGGGCCTCGACCACATGGCCTC
  CAGCATTGAGCGCATGGGCCAGACCATGGAGCGCATTGGCTCTGGCGTGGAGCGCATGGGTGCCGGCATG
  GGCTTCGGCCTTGAGCGCATGGCCGCTCCCATCGACCGTGTGGGCCAGACCATTGAGCGCATGGGCTCTG
  GCGTGGAGCGCATGGGCCCTGCCATCGAGCGCATGGGCCTGAGCATGGAGCGCATGGTGCCCGCAGGTAT
  GGGAGCTGGCCTGGAGCGCATGGGCCCCGTGATGGATCGCATGGCCACCGGCCTGGAGCGCATGGGCGCC
  AACAATCTGGAGCGGATGGGCCTGGAGCGCATGGGCGCCAACAGCCTCGAGCGCATGGGCCTGGAGCGCA
  TGGGTGCCAACAGCCTCGAGCGCATGGGCCCTGCCATGGGCCCGGCCCTGGGCGCTGGCATTGAGCGCAT
  GGGCCTGGCCATGGGTGGCGGTGGCGGTGCCAGCTTTGACCGTGCCATCGAGATGGAGCGTGGCAACTTC
  GGAGGAAGCTTCGCAGGTTCCTTTGGTGGAGCTGGAGGCCATGCTCCTGGGGTGGCCAGGAAGGCCTGCC
  AGATATTTGTGAGAAATCTGCCATTCGATTTCACATGGAAGATGCTAAAGGACAAATTCAACGAGTGCGG
  CCACGTGCTGTACGCCGACATCAAGATGGAGAATGGGAAGTCCAAGGGGTGTGGCGTGGTTAAGTTCGAG
  TCGCCAGAGGTGGCCGAGAGAGCCTGCCGGATGATGAATGGCATGAAGCTGAGTGGCCGAGAGATTGACG
  TTCGAATTGATAGAAACGCTTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_005968 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGANAAAATGGCGGCAGGNG
  GTCGAAGCGGCGGCGGAGGTGGCGGCGACGGAGATCAAAATGGAGGAAGAGAGCGGCGCG
  CCCGGCGTGCCGAGCGGCAACGGGGCTCCGGGCCCTAAGGGTGAAGGAGAACGACCTGCT
  CAGAATGAGAAGAGGAAGGAGAAAAACATAAAAAGAGGAGGCAATCGCTTTGAGCCATAT
  GCCAATCCAACTAAAAGATACAGAGCCTTCATTACAAACATACCTTTTGATGTGAAATGG
  CAGTCACTTAAAGACCTGGTTAAAGAAAAAGTTGGTGAGGTAACATACGTGGAGCTCTTA
  ATGGACGCTGAAGGAAAGTCAAGGGGATGTGCTGTTGTTGAATTCAAGATGGAAGAGAGC
  ATGAAAAAAGCTGCGGAAGTCCTAAACAAGCATAGTCTGAGCGGAAGACCACTGAAAGTC
  AAAGAAGATCCTGATGGTGAACATGCCAGGAGAGCAATGCAAAAGGTGATGGCTACGACT
  GGTGGGATGGGTATGGGACCAGGTGGCCCAGGAATGATTACTATCCCACCCAGTATCCTA
  AATAATCCCAACATCCCAAATGAGATTATCCATGCATTACAGGCTGGAAGACTTGGAAGC
  ACAGTATTTGTAGCAAATCTGGATTATAAAGTTGGCTGGAAGAAACTGAAGGAAGTATTT
  AGTATGGGCTGGGTGTGGTGGTCCGAGCANACATTCTTGAGATAAAGATGGAAAAGTCGT
  GGATAGGCACTGTTACTTTTGAACAGTCATTGAAGCTGTGCAGCCTTATCTATGTTCAAT
  GGCCAGCTGCTATTTGAAGACCAATGCCGTCAGATGGATGAAAGGGNCCTACAAAAGGNA
  GATTCTTCCTNCTGAGCGTCACAACACTNCCCATGGNNCTGGNGGNNATGNCATGGGGTA
  GGACAGNAGGGCANCCCATGTGGCCATCCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_005968 unedited
  NNNTTTCTTTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCAGG
  AACCGGTATTTATTATCAAAGTCATATTCGATGTCAACAAGATGCCACAACTACAAAAAA
  AATTGCGCACATTGCAATCTCAATGCAAACAGTCAAATGGAACCCCAGTCATTAAAAAAG
  TAATTCAAATTACCCCAAAAAGCAACTGAATTTTTTAAACATCTTTATACATCCAGCCAA
  CAAATTAAAATGGTTAACAAGAAAAAATACAAATTCAGAGGTCTCGTATCGATGTTTAAA
  AAAGGCAACTGCTTAAGCGTTTCTATCAATTCGAACGTCAATCTCTCGGCCACTCAGCTT
  CATGCCATTCATCATCCGGCAGGCTCTCTCGGCCACCTCTGGCGACTCGAACTTAACCAC
  ACCACACCCCTTGGACTTCCCATTCTCCATCTTGATGTCGGCGTACAGCACGTGGCCGCA
  CTCGTTGAATTTGTCCTTTAGCATCTTCCATGTGAAATCGAATGGCAGATTTCTCACAAA
  TATCTGGCAGGCCTTCCTGGCCACCCCAGGAGCATGGCCTCCAGCTCCACCAAAGGAACC
  TGCGAAGCTTCCTCCGAAGTTGCCACGCTCCATCTCGATGGCACGGTCAAAGCTGGCACC
  GNCACCGCCACCCATGGCCAGGCCCATGCGCTCAATGCCAGCGCCCAGGGCCGGGCCCAT
  GGCGGGGCCCATGCGCTCGAAGCTGTTGGGACCCATGCGCTNCAGGCCCATGCGCTCGAG
  GCTGTTGGCGCCCATGCGCTCCAGGCCATTCGCTTCAAATTGTTGCGGCCATGCGCTTCA
  GCCGGGGGCCATGCGATCATAACGGGGCCCTGCCTCCAGGCAGTTCCATACCTGGGGCAC
  CATGCGCTCATGCCAGGCCAGCCCTTATGGAAGGCCCTGCCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_005968
• Insert Size: 2350 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_005968.2, NP_005959.2
• RefSeq Size: 2547 bp
• RefSeq ORF: 2547 bp
• Locus ID: 4670
• UniProt ID: P52272
• Cytogenetics: 19p13.2
• Domains: RRM
• Protein Families: Druggable Genome
• Protein Pathways: Spliceosome
• Gene Summary: This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (1) encodes the longest isoform (a).