OriGene - CEBPB (NM_005194) cDNA Clone

OriGene Data

Vector:	pCMV6-AC	Insert Size:	Restriction Site: EcoRI-XhoI
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence
OTI Annotation:	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	ES Cell Differentiation/IPS Transcription Factors Druggable Genome
Protein Pathways:

Reference Data

RefSeq: NM_005194.2, NP_005185	RefSeq Size: 1837	RefSeq ORF: 1037
Synonyms : C/EBP-beta; CRP2; IL6DBP; LAP; NF-IL6; TCF5
LocusID: 1051	Cytogenetic: 20q13.1	Domains: BRLZ
Summary: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. [provided by RefSeq, Jul 2008].

The use of this clone has been cited in the following citations:

Herpes Simplex Virus Type 2 Infection of Human Epithelial Cells Induces CXCL9 Expression and CD4+ T Cell Migration via Activation of p38-CCAAT/Enhancer-Binding Protein-ß Pathway , Wenjie Huang, Kai Hu, Sukun Luo, Mudan Zhang, Chang Li, Wei Jin, Yalan Liu, George E. Griffin, Robin J. Shattock, and Qinxue Hu, J. Immunol., Jun 2012; 188: 6247 - 6257. [CEBPB ]

C/EBP-ß Modulates Transcription of Tubulointerstitial Nephritis Antigen in Obstructive Uropathy, Ping Xie, Lin Sun, Baibasawata Nayak, Yoshisuke Haruna, Fu-you Liu, Naoki Kashihara, and Yashpal S. Kanwar, . Am. Soc. Nephrol., Apr 2009; 20: 807 - 819. [CEBPB]

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CEBPB Mouse Clones

SKU	Description	Amount	Price	Shipping
MC208276	Mus musculus CCAAT/enhancer binding protein (C/EBP), beta (Cebpb) as transfection-ready DNA	10 ug	$380	Next day
MR227563	Myc-DDK-tagged ORF clone of Mus musculus CCAAT/enhancer binding protein (C/EBP), beta (Cebpb) as transfection-ready DNA	10 ug	$380	Next day
MG227563	GFP-tagged ORF clone of Mus musculus CCAAT/enhancer binding protein (C/EBP) beta (Cebpb) as transfection-ready DNA	10 ug	$420	3 weeks

CEBPB Rat Clones

SKU	Description	Amount	Price	Shipping
RN205240	NativeORF clone of Rattus norvegicus CCAAT/enhancer binding protein (C/EBP), beta (Cebpb) as transfection-ready DNA	10 ug	$380	13 weeks
RR205240	Myc-DDK-tagged ORF clone of Rattus norvegicus CCAAT/enhancer binding protein (C/EBP), beta (Cebpb) as transfection-ready DNA	10 ug	$380	Next day

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CEBPB (NM_005194) Human cDNA Clone

The use of this clone has been cited in the following citations:

CEBPB Mouse Clones

CEBPB Rat Clones

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