OriGene - CEBPA (NM_004364) cDNA Clone

OriGene Data

Vector:	pCMV6-XL5	Insert Size: 1200	Restriction Site:
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Annotation:	This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	ES Cell Differentiation/IPS Druggable Genome
Protein Pathways:	Pathways in cancer Acute myeloid leukemia

Reference Data

RefSeq: NM_004364.2, NP_004355	RefSeq Size: 2385	RefSeq ORF: 1077
Synonyms : C/EBP-alpha; CEBP
LocusID: 1050	Cytogenetic: 19q13.1
Summary: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells. [provided by RefSeq, Jul 2008].

The use of this clone has been cited in the following citations:

PU.1 and C/EBPa synergistically program distinct response to NF-{kappa}B activation through establishing monocyte specific enhancers, Fulai Jin, Yan Li, Bing Ren, and Rama Natarajan, PNAS, Mar 2011; 108: 5290 - 5295 [CEBPA]

Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyper proliferation and restores myeloid differentiation, Ayten Kandilci and Gerard C. Grosveld, Blood, Jun 2009; 10.1182/blood-2009-02-205443. [CEBPA]

More TrueClone Citations >>

CEBPA Mouse Clones

SKU	Description	Amount	Price	Shipping
MC203281	Mus musculus CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa) as transfection-ready DNA	10 ug	$165	Next day
MR205482	Myc-DDK-tagged ORF clone of Mus musculus CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa) as transfection-ready DNA	10 ug	$380	Next day
MG205482	GFP-tagged ORF clone of Mus musculus CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa) in a GFP expression vector	10 ug	$420	Next day

CEBPA Rat Clones

SKU	Description	Amount	Price	Shipping
RN203689	NativeORF clone of Rattus norvegicus CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa) as transfection-ready DNA	10 ug	$380	5 weeks
RR203689	Myc-DDK-tagged ORF clone of Rattus norvegicus CCAAT/enhancer binding protein (C/EBP), alpha (Cebpa) as transfection-ready DNA	10 ug	$380	5 weeks

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CEBPA (NM_004364) Human cDNA Clone

The use of this clone has been cited in the following citations:

CEBPA Mouse Clones

CEBPA Rat Clones

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