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Home TrueClone ACVR1B Clone

ACVR1B (NM_004302) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC108895 ACVR1B (untagged)-Human activin A receptor, type IB (ACVR1B), transcript variant 1 (10ug), NM_004302.3, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307816 Rabbit monoclonal antibody against ACVR1B(clone EPR4815), 100ul $325 Next Day
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Click here for the corresponding kinase deficient mutant clone.
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 3300 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseTransmembraneDruggable Genome
Protein Pathways: MAPK signaling pathwayCytokine-cytokine receptor interactionEndocytosisTGF-beta signaling pathwayAdherens junctionPathways in cancerMore Pathways >>
Reference Data
RefSeq: NM_004302.3, NP_004293
RefSeq Size: 4540 RefSeq ORF: 1518
Synonyms : ACTRIB; ACVRLK4; ALK4; SKR2
LocusID: 91 Cytogenetic: 12q13 Domains: Activin_recp, pkinase, TyrKc, S_TKc, GS
Summary: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010].

Transcript Variant: This variant (1) encodes isoform (a).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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