GLP2R (NM_004246) Human Untagged Clone

CAT#: SC111108

GLP2R (untagged)-Human glucagon-like peptide 2 receptor (GLP2R)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GLP2R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004246, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAAGCTGGGATCGAGCAGGGCAGGGCCTGGGAGAGGAAGCGCGGGACTCCTGCCTGGCGTCCACGAGC
  TGCCCATGGGCATCCCTGCCCCCTGGGGGACCAGTCCTCTCTCCTTCCACAGGAAGTGCTCTCTCTGGGC
  CCCTGGGAGGCCCTTCCTCACTCTGGTCCTGCTGGTTTCCATCAAGCAAGTTACAGGATCCCTCCTTGAG
  GAAACGACTCGGAAGTGGGCTCAGTACAAACAGGCATGTCTGAGAGACTTACTCAAGGAACCTTCTGGCA
  TATTTTGTAACGGGACATTTGATCAGTACGTGTGTTGGCCTCATTCTTCTCCTGGAAATGTCTCTGTACC
  CTGCCCTTCATACTTACCTTGGTGGAGTGAAGAGAGCTCAGGAAGGGCCTACAGACACTGCTTGGCTCAG
  GGGACTTGGCAGACGATAGAGAACGCCACGGATATTTGGCAGGATGACTCCGAATGCTCCGAGAACCACA
  GCTTCAAGCAAAACGTGGACCGTTATGCCTTGCTGTCAACCTTGCAGCTGATGTACACCGTGGGATACTC
  CTTCTCTCTTATCTCCCTCTTCCTGGCTCTCACCCTCCTCTTGTTTCTTCGAAAACTCCACTGCACGCGC
  AACTACATCCACATGAACTTGTTTGCTTCTTTCATCCTGAGAACCCTGGCTGTACTGGTGAAGGACGTCG
  TCTTCTACAACTCTTACTCCAAGAGGCCTGACAATGAGAATGGGTGGATGTCCTACCTGTCAGAGATGTC
  CACCTCCTGCCGCTCAGTCCAGGTTCTCTTGCATTACTTTGTGGGTGCCAATTACTTATGGCTGCTGGTT
  GAAGGCCTCTACCTCCACACGCTGCTGGAGCCCACAGTGCTTCCTGAGAGGCGGCTGTGGCCCAGATACC
  TGCTGTTGGGTTGGGCCTTCCCTGTGCTATTTGTTGTACCCTGGGGTTTCGCCCGTGCACACCTGGAGAA
  CACAGGGTGCTGGACAACAAATGGGAATAAGAAAATCTGGTGGATCATCCGAGGACCCATGATGCTCTGT
  GTAACAGTCAATTTCTTCATCTTCCTGAAAATTCTCAAGCTTCTCATTTCTAAGCTCAAAGCTCATCAAA
  TGTGCTTCAGAGATTATAAATACAGATTGGCAAAATCAACACTGGTCCTCATTCCTTTATTGGGCGTTCA
  TGAGATCCTCTTCTCTTTCATCACTGATGATCAAGTTGAAGGATTTGCAAAACTTATACGACTTTTCATT
  CAGTTGACACTGAGCTCCTTTCATGGGTTCCTGGTGGCCTTGCAGTATGGTTTTGCCAATGGAGAAGTGA
  AGGCTGAGCTGCGGAAATACTGGGTCCGCTTCTTGCTAGCCCGCCACTCAGGCTGCAGAGCCTGTGTCCT
  GGGGAAGGACTTCCGGTTCCTAGGAAAATGTCCCAAGAAGCTCTCGGAAGGAGATGGCGCTGAGAAGCTT
  CGGAAGCTGCAGCCCTCACTTAACAGTGGGCGGCTCCTACATCTAGCCATGCGAGGTCTTGGGGAGCTGG
  GCGCCCAGCCCCAACAGGACCATGCACGCTGGCCCCGGGGCAGCAGCCTGTCCGAGTGCAGTGAGGGGGA
  TGTCACCATGGCCAACACCATGGAGGAGATTCTGGAAGAGAGTGAGATCTAG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004246 unedited
  GATTTTGTATACGACTCACTATAGGGCGGCCCGCGATTCGGCACGAGCTCAGACACTCTC
  GGCGCAGCGTGGAGAGGATTTGTGCAAACATTTCCTCTGTGGACCAAGAGGAATGCAAGA
  GGAGGCTGCCTGCGGTGCATCTTGGACGGCTAGAGAGATGTACCCCTACTTGTGAAGGTG
  CACGAGGAAGATGAAGCTGGGATCGAGCAGGGCAGGGCCTGGGAGAGGAAGCGCGGGACT
  CCTGCCTGGCGTCCACGAGCTGCCCATGGGCATCCCTGCCCCCTGGGGGACCAGTCCTCT
  CTCCTTCCACAGGAAGTGCTCTCTCTGGGCCCCTGGGAGGCCCTTCCTCACTCTGGTCCT
  GCTGGTTTCCATCAAGCAAGTTACAGGATCCCTCCTTGAGGAAACGACTCGGAAGTGGGC
  TCAGTACAAACAGGCATGTCTGAGAGACTTACTCAAGGAACCTTCTGGCATATTTTGTAA
  CGGGACATTTGATCAGTACGTGTGTTGGCCTCATTCTTCTCCTGGAAATGTCTCTGTACC
  CTGCCCTTCATACTTACCTTGGTGGAGTGAAGAGAGCTCAGGAAGGGCCTACAGACACTG
  CTTGGCTCAGGGGACTTGGCAGACGATAGAGAACGCCACGGATATTTGGCAGGATGACTC
  CGAGTGCTCCGAGAACCACAGCTTCAAGCAAAACGTGGATCGTTATGCCTTGCTGTCAAC
  CTTGCAGCTGATGTACACCGTGGGATACTCCTTCTCTCTTATCTCCCTCTTCCTGGCTCT
  CACCCTCCTCTTGNTTCTTCGAAAACTCCACTGCACGCGCAACTACATCCACATGAACTT
  GNTTGCTTCTTTCATNCTGAGAACCCTGNCTGTACTGGTGAAGGACGTCGTCTTCTACAA
  CTCTACTNCAGAGGCCTGACATGAGATGGNTGGATGTCCTACTGTCAGAGAGTCCACTCC
  TGCGCTCAGTCAGNTCTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004246
• Insert Size: 4700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_004246.1, NP_004237.1
• RefSeq Size: 1662 bp
• RefSeq ORF: 1662 bp
• Locus ID: 9340
• UniProt ID: O95838
• Cytogenetics: 17p13.1
• Domains: 7tm_2, HormR
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: This gene encodes a G protein-coupled receptor that is closely related to the glucagon receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. [provided by RefSeq, Dec 2014]