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Home TrueClone EIF4EBP1 Clone

EIF4EBP1 (NM_004095) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC122669 EIF4EBP1 (untagged)-Human eukaryotic translation initiation factor 4E binding protein 1 (EIF4EBP1) (10ug) NM_004095.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA300488 Rabbit Monoclonal Antibody against EIF4EBP1 (Clone Y329), 100ul $325 3-7 Days
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Also for EIF4EBP1 (NM_004095)
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 900 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_004095.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Pathways: ErbB signaling pathwaymTOR signaling pathwayInsulin signaling pathwayAcute myeloid leukemia
Reference Data
RefSeq: NM_004095.2, NP_004086
RefSeq Size: 895 RefSeq ORF: 357
Synonyms : 4E-BP1; 4EBP1; BP-1; PHAS-I
LocusID: 1978 Cytogenetic: 8p12
Summary: This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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