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 Home TrueClone DLK1 Clone

DLK1 (NM_003836) Human cDNA Clone

Specifications Citations (2) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC127962 Homo sapiens delta-like 1 homolog (Drosophila) (DLK1) as transfection-ready DNA NM_003836.4, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307339 Rabbit monoclonal antibody against DLK(clone EPR3486(2)), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 1700 Restriction Site: NotI-NotI
Sequence Data: 5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSTransmembraneDruggable Genome
Reference Data
RefSeq: NM_003836.4, NP_003827
 RefSeq Size: 1532 RefSeq ORF: 1152
Synonyms : Delta1; DLK; DLK-1; FA1; pG2; Pref-1; PREF1; ZOG
LocusID: 8788 Cytogenetic: 14q32 Domains: EGF_CA, EGF, EGF
Summary: This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. [provided by RefSeq, Mar 2010].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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