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Home TrueClone TGFBR2 Clone

TGFBR2 (NM_003242) Human Kinase Deficient Mutant

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC323450 TGFBR2 (untagged)-Kinase deficient mutant (K277M) of Human transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 2 (10ug) NM_003242.4, 10ug $850 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA319109 Rabbit polyclonal anti-TGF-beta Receptor II antibody, 100ug $325 3-7 Days
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Click here for the corresponding wild type clone.

OriGene Data
Vector:pCMV6-XL5 Insert Size: 4350 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          Kinase domain sequence
OTI Annotation: This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseTransmembraneDruggable Genome
Protein Pathways: MAPK signaling pathwayCytokine-cytokine receptor interactionEndocytosisTGF-beta signaling pathwayAdherens junctionPathways in cancerMore Pathways >>
Reference Data
RefSeq: NM_003242.4, NP_003233
RefSeq Size: 4639 RefSeq ORF: 1704
Synonyms : AAT3; FAA3; LDS1B; LDS2B; MFS2; RIIC; TAAD2; TGFbeta-RII; TGFR-2
LocusID: 7048 Cytogenetic: 3p22 Domains: pkinase, TyrKc, S_TKc
Summary:

Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region compared to variant 1. The resulting protein (isoform B) is shorter than isoform A.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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