OriGene - CCL1 (NM_002981) cDNA Clone

OriGene Data

Vector:	pCMV6-XL5	Insert Size: 400	Restriction Site:
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence
OTI Annotation:	The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	Secreted Protein Druggable Genome
Protein Pathways:	Cytokine-cytokine receptor interaction Chemokine signaling pathway

Reference Data

RefSeq: NM_002981.1, NP_002972	RefSeq Size: 542	RefSeq ORF: 291
Synonyms : I-309; P500; SCYA1; SISe; TCA3
LocusID: 6346	Cytogenetic: 17q12
Summary: This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq, Jul 2008].

TrueClone Citations:

MPN patients harbor recurrent truncating mutations in transcription factor NF-E2, Jonas S. Jutzi, Ruzhica Bogeska, Gorica Nikoloski, Corina A. Schmid, Thalia S. Seeger, Frank Stegelmann, Sven Schwemmers, Albert Gründer, Jan C. Peeken, Monika Gothwal, Julius Wehrle, Konrad Aumann, Kamar Hamdi, Christine Dierks, Wei Wang, Konstanze Döhner, Joop H. Jansen, and Heike L. Pahl, J. Exp. Med., May 2013; 210: 1003 - 1019. [MAFG]

The Human Tim-Tipin Complex Interacts Directly with DNA Polymerase and Stimulates Its Synthetic Activity, Valentina Aria, Mariarita De Felice, Roberta Di Perna, Shuji Uno, Hisao Masai, Juhani E. Syväoja, Barbara van Loon, Ulrich Hübscher, and Francesca M. Pisani, J. Biol. Chem., May 2013; 288: 12742 - 12752. [TIPIN]

Reciprocal Regulation of Protein Kinase and Pyruvate Kinase Activities of Pyruvate Kinase M2 by Growth Signals, Xueliang Gao, Haizhen Wang, Jenny J. Yang, Jing Chen, Jiang Jie, Liangwei Li, Yinwei Zhang, and Zhi-Ren Liu, J. Biol. Chem., May 2013; 288: 15971 - 15979. [PKM2]

Prospero-related homeobox 1 (Prox1) functions as a novel modulator of retinoic acid-related orphan receptors a- and -mediated transactivation, Yukimasa Takeda and Anton M. Jetten, Nucleic Acids Res., May 2013; 10.1093/nar/gkt447. [Prox1 ]

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia, Hanna L. M. Rajala, Samuli Eldfors, Heikki Kuusanmäki, Arjan J. van Adrichem, Thomas Olson, Sonja Lagström, Emma I. Andersson, Andres Jerez, Michael J. Clemente, Yiyi Yan, Dan Zhang, Andy Awwad, Pekka Ellonen, Olli Kallioniemi, Krister Wennerberg, Kimmo Porkka, Jaroslaw P. Maciejewski, Thomas P. Loughran, Jr, Caroline Heckman, and Satu Mustjoki, Blood, May 2013; 121: 4541 - 4550. [STAT5B]

Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites, Isabelle Bally, Sarah Ancelet, Christine Moriscot, Florence Gonnet, Alberto Mantovani, Régis Daniel, Guy Schoehn, Gérard J. Arlaud, and Nicole M. Thielens, PNAS, May 2013; 110: 8650 - 8655. [C1qA]

MicroRNA-22 and promoter motif polymorphisms at the Chga locus in genetic hypertension: functional and therapeutic implications for gene expression and the pathogenesis of hypertension, Ryan S. Friese, Angelina E. Altshuler, Kuixing Zhang, Jose Pablo Miramontes-Gonzalez, C. Makena Hightower, Martin L. Jirout, Rany M. Salem, Jiaur R. Gayen, Nitish R. Mahapatra, Nilima Biswas, Mo Cale, Sucheta M. Vaingankar, Hyung-Suk Kim, Maïté Courel, Laurent Taupenot, Michael G. Ziegler, Nicholas J. Schork, Michal Pravenec, Sushil K. Mahata, Geert W. Schmid-Schönbein, and Daniel T. O'Connor, Hum. Mol. Genet., May 2013; 10.1093/hmg/ddt213. [HAND1]

Development of LC/MS/MS, High-Throughput Enzymatic and Cellular Assays for the Characterization of Compounds That Inhibit Kynurenine Monooxygenase (KMO), Dirk Winkler, Maria Beconi, Leticia M. Toledo-Sherman, Michael Prime, Andreas Ebneth, Celia Dominguez, and Ignacio Muñoz-Sanjuan, J Biomol Screen, May 2013; 10.1177/1087057113489731. [KMO]

More TrueClone Citations >>

CCL1 Mouse Clones

SKU	Description	Amount	Price	Shipping
MC209361	Mus musculus chemokine (C-C motif) ligand 1 (Ccl1) as transfection-ready DNA	10 ug	$380	2 weeks
MR217886	Myc-DDK-tagged ORF clone of Mus musculus chemokine (C-C motif) ligand 1 (Ccl1) as transfection-ready DNA	10 ug	$380	2 weeks
MG217886	GFP-tagged ORF clone of Mus musculus chemokine (C-C motif) ligand 1 (Ccl1) as transfection-ready DNA	10 ug	$420	3 weeks

Don't see the species of your interest?
Use Blue Heron gene synthesis and make clone in any of OriGene's expression vectors.

CCL1 (NM_002981) Human cDNA Clone

TrueClone Citations:

CCL1 Mouse Clones

Product Manuals

MSDS

FAQs