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Home TrueClone MSH3 Clone

MSH3 (NM_002439) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC309971 MSH3 (untagged)-Human mutS homolog 3 (E. coli) (MSH3) (10ug), NM_002439.2, 10ug $980 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA310696 Rabbit Monoclonal antibody against MSH3, 100ul $325 3-7 Days
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 4500 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_002439.2.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Stem cell - PluripotencyDruggable Genome
Protein Pathways: Mismatch repairPathways in cancerColorectal cancer
Reference Data
RefSeq: NM_002439.2, NP_002430
RefSeq Size: 4645 RefSeq ORF: 3414
Synonyms : DUP; MRP1
LocusID: 4437 Cytogenetic: 5q11 Domains: MUTSac, MutS_I, MUTSd, MutS_II
Summary: The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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