Clusterin (CLU) (NM_001831) Human Untagged Clone

CAT#: SC118977

CLU (untagged)-Human clusterin (CLU), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: Clusterin
• Synonyms: AAG4; APO-J; APOJ; CLI; CLU1; CLU2; KUB1; NA1/NA2; SGP-2; SGP2; SP-40; TRPM-2; TRPM2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118977 sequence for NM_001831 edited (data generated by NextGen Sequencing)
  ATGCAGGTTTGCAGCCAGCCCCAAAGGGGGTGTGTGCGCGAGCAGAGCGCTATAAATACG
  GCGCCTCCCAGTGCCCACAACGCGGCGTCGCCAGGAGGAGCGCGCGGGCACAGGGTGCCG
  CTGACCGAGGCGTGCAAAGACTCCAGAATTGGAGGCATGATGAAGACTCTGCTGCTGTTT
  GTGGGGCTGCTGCTGACCTGGGAGAGTGGGCAGGTCCTGGGGGACCAGACGGTCTCAGAC
  AATGAGCTCCAGGAAATGTCCAATCAGGGAAGTAAGTACGTCAATAAGGAAATTCAAAAT
  GCTGTCAACGGGGTGAAACAGATAAAGACTCTCATAGAAAAAACAAACGAAGAGCGCAAG
  ACACTGCTCAGCAACCTAGAAGAAGCCAAGAAGAAGAAAGAGGATGCCCTAAATGAGACC
  AGGGAATCAGAGACAAAGCTGAAGGAGCTCCCAGGAGTGTGCAATGAGACCATGATGGCC
  CTCTGGGAAGAGTGTAAGCCCTGCCTGAAACAGACCTGCATGAAGTTCTACGCACGCGTC
  TGCAGAAGTGGCTCAGGCCTGGTTGGCCGCCAGCTTGAGGAGTTCCTGAACCAGAGCTCG
  CCCTTCTACTTCTGGATGAATGGTGACCGCATCGACTCCCTGCTGGAGAACGACCGGCAG
  CAGACGCACATGCTGGATGTCATGCAGGACCACTTCAGCCGCGCGTCCAGCATCATAGAC
  GAGCTCTTCCAGGACAGGTTCTTCACCCGGGAGCCCCAGGATACCTACCACTACCTGCCC
  TTCAGCCTGCCCCACCGGAGGCCTCACTTCTTCTTTCCCAAGTCCCGCATCGTCCGCAGC
  TTGATGCCCTTCTCTCCGTACGAGCCCCTGAACTTCCACGCCATGTTCCAGCCCTTCCTT
  GAGATGATACACGAGGCTCAGCAGGCCATGGACATCCACTTCCATAGCCCGGCCTTCCAG
  CACCCGCCAACAGAATTCATACGAGAAGGCGACGATGACCGGACTGTGTGCCGGGAGATC
  CGCCACAACTCCACGGGCTGCCTGCGGATGAAGGACCAGTGTGACAAGTGCCGGGAGATC
  TTGTCTGTGGACTGTTCCACCAACAACCCCTCCCAGGCTAAGCTGCGGCGGGAGCTCGAC
  GAATCCCTCCAGGTCGCTGAGAGGTTGACCAGGAAATACAACGAGCTGCTAAAGTCCTAC
  CAGTGGAAGATGCTCAACACCTCCTCCTTGCTGGAGCAGCTGAACGAGCAGTTTAACTGG
  GTGTCCCGGCTGGCAAACCTCACGCAAGGCGAAGACCAGTACTATCTGCGGGTCACCACG
  GTGGCTTCCCACACTTCTGACTCGGACGTTCCTTCCGGTGTCACTGAGGTGGTCGTGAAG
  CTCTTTGACTCTGATCCCATCACTGTGACGGTCCCTGTAGAAGTCTCCAGGAAGAACCCT
  AAATTTATGGAGACCGTGGCGGAGAAAGCGCTGCAGGAATACCGCAAAAAGCACCGGGAG
  GAGTGA
  
  Clone variation with respect to NM_001831.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001831 unedited
  AGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCTTTCCGC
  GGCATTCTTTGGGCGTGAGTCATGCAGGTTTGCAGCCAGCCCCAAAGGGGGTGTGTGCGC
  GAGCAGAGCGCTATAAATACGGCGCCTCCCAGTGCCCACAACGCGGCGTCGCCAGGAGGA
  GCGCGCGGGCACAGGGTGCCGCTGACCGAGGCGTGCAAAGACTCCAGAATTGGAGGCATG
  ATGAAGACTCTGCTGCTGTTTGTGGGGCTGCTGCTGACCTGGGAGAGTGGGCAGGTCCTG
  GGGGACCAGACGGTCTCAGACAATGAGCTCCAGGAAATGTCCAATCAGGGAAGTAAGTAC
  GTCAATAAGGAAATTCAAAATGCTGTCAACGGGGTGAAACAGATAAAGACTCTCATAGAA
  AAAACAAACGAAGAGCGCAAGACACTGCTCAGCAACCTAGAAGAAGCCAAGAAGAAGAAA
  GAGGATGCCCTAAATGAGACCAGGGAATCAGAGACAAAGCTGAAGGAGCTCCCAGGAGTG
  TGCAATGAGACCATGATGGCCCTCTGGGAAGAGTGTAAGCCCTGCCTGAAACAGACCTGC
  ATGAAGTTCTACGCACGCGTCTGCAGAAGTGGCTCANGCCTGGTTGGCCGCCAGCTTGAG
  GAGTTCCTGAACCAGAGCTCGCCCTTCTACTTCTGGATGAATGGTGACCGCATCGACTCC
  CTGCTGGAGAACGACCGGCAGCAGACGCACATGCTGGNATGTCATGCAGGACCACTTCAG
  CCGCGCGTCCAGCATCATAGACGAGCTCTTCAGNACAGTTNCTTCACCCGGGAGCCCCAG
  ATACCTACACTATNNNNNN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001831 unedited
  AGGANACCGGGTCACAGGGCATGCCACCCGGGTATCTGTTCAGGAAAACAGCTATGACCG
  CGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTCCACCCCACAAAACATTTTTATTGAATTATTTGCAGGCA
  GGAACAATTTTTTTCTTCCCATGAACACCAAATTCAAGTGTTAAAGTGCAGGATCCAAAC
  CGGGGAAAGGCTGGGCGGATTTGGGGCCCCGGAGGCCGGGGCCTGTTTACTTGGTGACCT
  GCAAACCCCTCTCGGGGGGGCCCCCCCCCATCTTGGGGGGAGCTGGACTCAAATCCCCCC
  GTGGGGGCAAAAACAAAATCCACATCTCACTCCTCCCGGTGCTTTTTGGGGTTTTCCGGC
  CGCGCTTTCCCCCCCACGGTCCCCAAAAATTTAGGGTTCTCCCGGGAAACTTCTACGGGG
  ACCGTCACAGGGGGGGGTTCAAAATCAAAAAACTTCACAACCCCCCCAGTGACCCCGGAA
  GGAACGTCCGAATCAAAAGTGTGGGAACCCACCGTGGTCACCCCAAAAAAAAACGGGTCT
  CTCCCCTTGCGGGGAGTTTCCCCCCCCGGGACACCAATTAAACGGGCCGTTTCACCGCCC
  CCAAAAGGGGGGAGGGGGTGAACACCCTCCCCCGGGTGGGAAATTTAACCACCCCTTGTT
  TTTTCGCGGGCCCCCCCCCCACCACCCGAGGGGAATTCCTCAACCTCCCACACAAACATA
  AATCGGGGGGGGGTTGTTTGGGGGAACAACTCACACAAAAATATTTCTCCCGGCAATCGA
  AACAAGAGGTTTTCTTTCCAGGAAAAACCCGAGGGGTTGTGGACGAGATCCCCCAAACAA
  AAAGAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001831
• Insert Size: 1900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001831.2, NP_001822.2
• RefSeq Size: 2859 bp
• RefSeq ORF: 1506 bp
• Locus ID: 1191
• UniProt ID: P10909
• Cytogenetics: 8p21.1
• Domains: CLa
• Protein Families: Druggable Genome, Secreted Protein
• Gene Summary: The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants.[provided by RefSeq, May 2011]
  Transcript Variant: This variant (1) encodes the functional protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.