Over 1000 citations of OriGene cDNA clones

MET Receptor Sequence Variants R970C and T992I Lack Transforming Capacity Cancer Res., Aug 2010; 70: 6233 - 6237 [MET]

Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a Mol. Pharmacol., Aug 2010; 78: 226 - 236 [ZBTB10]

Tumor Lymphangiogenesis and Metastasis to Lymph Nodes Induced by Cancer Cell Expression of Podoplanin Am. J. Pathol., Aug 2010; 177: 1004 - 1016 [PDPN]

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2V617F-independent overexpression of NF-E2 Blood, Jul 2010; 116: 254 - 266 [RUNX1]

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HIF1A (NM_001530) Human cDNA Clone

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Cat. No.

Ref. ID

Description

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SC119189

NM_001530

Homo sapiens hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) (HIF1A), transcript variant 1 as transfection-ready DNA NM_001530.2

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The use of this clone has been cited in the linked publication

Also for HIF1A (NM_001530)

OriGene TrueClone Data

Vector:	pCMV6-XL5	Insert Size: 4000	Restriction Site: NotI-NotI
Sequence Data:	Edited Nucleotide Sequence 5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.

Reference Data

RefSeq: NM_001530.2, NP_001521	RefSeq Size: 3958	RefSeq ORF: 2481
Synonyms : bHLHe78; HIF-1alpha; HIF1; HIF1-ALPHA; MOP1; PASD8
LocusID: 3091	Cytogenetic: 14q23.2	Domains: PAS, HLH, PAC
Summary: Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cultured under reduced oxygen tension that plays an essential role in cellular and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator (ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq]. Transcript Variant: This variant (1) encodes the predominant isoform (1).