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Home TrueClone TP73 Clone

TP73 (NM_001126240) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC323148 TP73 (untagged)-Human tumor protein p73 (TP73), transcript variant 2 (10ug), NM_001126240.1, 10ug $880 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA300559 Rabbit Monoclonal Antibody against TP73 (Clone EP436Y), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6 Entry Insert Size: 2800 Restriction Site:
Sequence Data: 5' Read Nucleotide Sequence          CHROMATOGRAMS Chromatogram
OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001126240.1.
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Transcription FactorsDruggable Genome
Protein Pathways: p53 signaling pathwayNeurotrophin signaling pathway
Reference Data
RefSeq: NM_001126240.1, NP_001119712
RefSeq Size: RefSeq ORF: 1763
Synonyms : P73
LocusID: 7161 Cytogenetic: 1p36.3
Summary: This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined. [provided by RefSeq, Feb

Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (b, also known as deltaN p73 alpha) has a shorter and distinct N-terminus compared to isoform a.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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