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Home TrueClone PLAGL1 Clone

PLAGL1 (NM_001080951) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC315954 PLAGL1 (untagged)-Human pleiomorphic adenoma gene-like 1 (PLAGL1), transcript variant 3 (10ug), NM_001080951.1, 10ug $680 3 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA310761 Rabbit Monoclonal antibody against PLAGL1, 100ul $325 3-7 Days
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Also for PLAGL1 (NM_001080951)
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OriGene Data
Vector:pCMV6-XL Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Transcription Factors
Reference Data
RefSeq: NM_001080951.1, NP_001074420
RefSeq Size: 3284 RefSeq ORF: 1392
Synonyms : LOT1; ZAC; ZAC1
LocusID: 5325 Cytogenetic: 6q24
Summary: This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. [provided by RefSeq, Oct 2010].

Transcript Variant: This variant (3) differs in the 5' UTR and contains an alternate exon in the CDS compared to variant 1. The resulting isoform (2) is longer and has an extended N-terminus compared to isoform 1. Variants 2, 3, 4, 5, 6, 10, 12, 15, 16, 17, 18, 19 and 20 all encode the same isoform (2).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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