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Home TrueClone RXRG Clone

RXRG (NM_001009598) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC301412 RXRG (untagged)-Human retinoid X receptor, gamma (RXRG), transcript variant 2 (10ug), NM_001009598.1, 10ug $380 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA309232 Mouse Anti-Retinoid X Receptor, g-Isotype Antibody, 100ul $325 3-7 Days
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 600 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_001009598.1.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Nuclear Hormone ReceptorTranscription FactorsDruggable Genome
Protein Pathways: PPAR signaling pathwayAdipocytokine signaling pathwayPathways in cancerThyroid cancerSmall cell lung cancerNon-small cell lung cancer
Reference Data
RefSeq: NM_001009598.1, NP_001009598
RefSeq Size: 633 RefSeq ORF: 102
Synonyms : NR2B3; RXRC
LocusID: 6258 Cytogenetic: 1q22
Summary: This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010].

Transcript Variant: This variant (2) includes an alternate exon, compared to variant 1, that causes a frameshift. The resulting protein (isoform b) is shorter and has a distinct C-terminus, compared to isoform a. Isoform b represents a polypeptide with a deduced amino acid sequence that has not been experimentally demonstrated to exist.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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