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Home TrueClone CD44 Clone

CD44 (NM_001001391) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC125340 CD44 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human CD44 molecule (Indian blood group) (CD44), (10ug), NM_001001391.1, 10ug $540 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA307654 Rabbit monoclonal antibody against CD44(clone EPR4773), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 2000 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
OTI Disclaimer: The sequence of an 'OriGene Unique Variant' differs significantly from the associated reference. It represents a novel splice variant from the same gene locus of the reference. Although such variants are true transcripts and present opportunity for discoveries, they are not yet curated by NCBI and should not be used if the exact reference accession sequence is required.
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Stem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSTransmembraneAdult stem cellsCancer stem cellsEmbryonic stem cellsDruggable Genome
Protein Pathways: ECM-receptor interactionHematopoietic cell lineage
Reference Data
RefSeq: NM_001001391.1, NP_001001391
RefSeq Size: 4605 RefSeq ORF: 1086
Synonyms : CDW44; CSPG8; ECMR-III; HCELL; HUTCH-I; IN; LHR; MC56; MDU2; MDU3; MIC4; Pgp1
LocusID: 960 Cytogenetic: 11p13
Summary: The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (4) lacks multiple coding-exons compared to variant 1. The translation remains in-frame. The resulting isoform (4) lacks an internal segment, as compared to isoform 1.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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