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Home TrueClone PDE1B Clone

PDE1B (NM_000924) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC310288 PDE1B (untagged)-Human phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1 (10ug) NM_000924.2, 10ug $680 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA503325 PDE1B mouse monoclonal antibody,clone 6B9, 100ul $379 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 1800 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Annotation: The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Purine metabolismCalcium signaling pathwayProgesterone-mediated oocyte maturation
Reference Data
RefSeq: NM_000924.2, NP_000915
RefSeq Size: 3236 RefSeq ORF: 1611
Synonyms : PDE1B1; PDES1B
LocusID: 5153 Cytogenetic: 12q13 Domains: PDEase, HDc
Summary: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011].

Transcript Variant: This variant (1) encodes the longest isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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