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Home TrueClone BCL2 Clone

BCL2 (NM_000633) Human cDNA Clone

Specifications Citations (4) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC125546 BCL2 (untagged)-Human B-cell CLL/lymphoma 2 (BCL2), nuclear gene encoding mitochondrial protein, transcript variant alpha (10ug), NM_000633.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA306171 Rabbit Polyclonal Bcl-2 Antibody, 100ug $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 3050 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSTransmembraneStem cell - PluripotencyDruggable Genome
Protein Pathways: ApoptosisFocal adhesionNeurotrophin signaling pathwayAmyotrophic lateral sclerosis (ALS)Pathways in cancerColorectal cancerMore Pathways >>
Reference Data
RefSeq: NM_000633.2, NP_000624
RefSeq Size: 6492 RefSeq ORF: 1359
Synonyms : Bcl-2; PPP1R50
LocusID: 596 Cytogenetic: 18q21.3
Summary: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (alpha) represents the longer transcript and encodes the longer isoform (alpha).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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