FBP1 (NM_000507) Human Untagged Clone

CAT#: SC322529

FBP1 (untagged)-Human fructose-1,6-bisphosphatase 1 (FBP1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBP1
• Synonyms: FBP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for SC322529 GCACCACGAGCGCTGCGGACACTCGGGGCGGCAGTCGGTCTGTCAGTCCTCCCGCCAGGT
  CCCGCGGCCCGCACCTGCCGCCCGCACCTGCAGCTCCGCACCTGCGGCCAGTGCCTACTG
  CCCTCTCTTGCCGCCCGCACCTGCAGCCCCGCACCTGCCGCTTGCACCTGCAGCCCCGCG
  CTCTACCCGGTTCAAGCATGGCTGACCAGGCGCCCTTCGACACGGACGTCAACACCCTGA
  CCCGCTTCGTCATGGAGGAGGGCAGGAAGGCCCGCGGCACGGGCGAGTTGACCCAGCTGC
  TCAACTCGCTCTGCACAGCAGTCAAAGCCATCTCTTCGGCGGTGCGCAAGGCGGGCATCG
  CGCACCTCTATGGCATTGCTGGTTCTACCAACGTGACAGGTGATCAAGTTAAGAAGCTGG
  ACGTCCTCTCCAACGACCTGGTTATGAACATGTTAAAGTCATCCTTTGCCACGTGTGTTC
  TCGTGTCAGAAGAAGATAAACACGCCATCATAGTGGAACCGGAGAAAAGGGGTAAATATG
  TGGTCTGTTTTGATCCCCTTGATGGATCTTCCAACATCGATTGCCTTGTGTCCGTTGGAA
  CCATTTTTGGCATCTATAGAAAGAAATCAACTGATGAGCCTTCTGAGAAGGATGCTCTGC
  AACCAGGCCGGAACCTGGTGGCAGCCGGCTACGCACTGTATGGCAGTGCCACCATGCTGG
  TCCTTGCCATGGACTGTGGGGTCAACTGCTTCATGCTGGACCCGGCCATCGGGGAGTTCA
  TTTTGGTGGACAAGGATGTGAAGATAAAAAAGAAAGGTAAAATCTACAGCCTTAACGAGG
  GCTACGCCAGGGACTTTGACCCTGCCGTCACTGAGTACATCCAGAGGAAGAAGTTCCCCC
  CAGATAATTCAGCTCCTTATGGGGCCCGGTATGTGGGCTCCATGGTGGCTGATGTTCATC
  GCACTCTGGTCTACGGAGGGATATTTCTGTACCCCGCTAACAAGAAGAGCCCCAATGGAA
  AGCTGAGACTGCTGTACGAATGCAACCCCATGGCCTACGTCATGGAGAAGGCTGGGGGAA
  TGGCCACCACTGGGAAGGAGGCCGTGTTAGACGTCATTCCCACAGACATTCACCAGAGGG
  CGCCGGTGATCTTGGGATCCCCCGACGACGTGCTCGAGTTCCTGAAGGTGTATGAGAAGC
  ACTCTGCCCAGTGAGCACCTGCCCTGCCTGCATCCGGAGAATTGCCTCTACCTGGACCTT
  TTGTCTCACACAGCAGTACCCTGACCTGCTGTGCACCTTACATTCCTAGAGAGCAGAAAT
  AAAAAGCATGACTATTTCCACCATCAAATGCTGTAGAATGCTTGGCACTCCCTAACCAAA
  TGCTGTCTCCATAATGCCACTGGTGTTAAGATATATTTTGAGTGGATGGAGGAGAAATAA
  ACTTATTCCTCCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_000507
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000507.2, NP_000498.2
• RefSeq Size: 1527 bp
• RefSeq ORF: 1017 bp
• Locus ID: 2203
• UniProt ID: P09467
• Cytogenetics: 9q22.32
• Domains: FBPase
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Fructose and mannose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Pentose phosphate pathway
• Gene Summary: Fructose-1,6-bisphosphatase 1, a gluconeogenesis regulatory enzyme, catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein.