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Home TrueClone LAMA2 Clone

LAMA2 (NM_000426) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC300068 LAMA2 (untagged)-Human laminin, alpha 2 (LAMA2), transcript variant 1 (10ug), NM_000426.2, 10ug $5620 11 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA314143 Rabbit polyclonal anti-LAMA2 antibody, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Focal adhesionECM-receptor interactionPathways in cancerSmall cell lung cancerHypertrophic cardiomyopathy (HCM)Arrhythmogenic right ventricular cardiomyopathy (ARVC)More Pathways >>
Reference Data
RefSeq: NM_000426.2, NP_000417
RefSeq Size: 9649 RefSeq ORF: 9369
Synonyms : LAMM
LocusID: 3908 Cytogenetic: 6q22
Summary: Laminin, an extracellular protein, is a major component of the basement membrane. It is thought to mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. It is composed of three subunits, alpha, beta, and gamma, which are bound to each other by disulfide bonds into a cross-shaped molecule. This gene encodes the alpha 2 chain, which constitutes one of the subunits of laminin 2 (merosin) and laminin 4 (s-merosin). Mutations in this gene have been identified as the cause of congenital merosin-deficient muscular dystrophy. Two transcript variants encoding different proteins have been found for this gene. [provided by RefSeq, Jul 2008].

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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