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Home TrueClone TNNI3 Clone

TNNI3 (NM_000363) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC119930 TNNI3 (untagged)-Human troponin I type 3 (cardiac) (TNNI3) (10ug), NM_000363.2, 10ug $380 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA500057 TNNI3 (Cardiac Troponin I) mouse monoclonal antibody, clone 4E5, 100ul $379 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2250 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSStem cell - PluripotencyDruggable Genome
Protein Pathways: Cardiac muscle contractionHypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy
Reference Data
RefSeq: NM_000363.2, NP_000354
RefSeq Size: 866 RefSeq ORF: 633
Synonyms : CMD1FF; CMD2A; CMH7; cTnI; RCM1; TNNC1
LocusID: 7137 Cytogenetic: 19q13.4
Summary: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). [provided by RefSeq, Jul


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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