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Home TrueClone MYBPC3 Clone

MYBPC3 (NM_000256) Human cDNA Clone

Specifications Citations (0) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC300037 MYBPC3 (untagged)-Human myosin binding protein C, cardiac (MYBPC3), NM_000256.2, 10ug $980 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA314224 Rabbit polyclonal anti-MYBPC3 antibody, 100ul $325 3 Weeks
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OriGene Data
Vector:pCMV6 Entry QM Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          CHROMATOGRAMS Chromatogram
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Hypertrophic cardiomyopathy (HCM)Dilated cardiomyopathy
Reference Data
RefSeq: NM_000256.2, NP_000247
RefSeq Size: 4200 RefSeq ORF: 3825
Synonyms : CMD1MM; CMH4; FHC; LVNC10; MYBP-C
LocusID: 4607 Cytogenetic: 11p11.2
Summary: MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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